Compile Data Set for Download or QSAR
Report error Found 104 Enz. Inhib. hit(s) with all data for entry = 8628
TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408950BDBM408950(Methyl 1-(2-cyclobutyl-N-((4'-methoxy-3'- methyl-[...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408951BDBM408951(Methyl 1-(2-cyclopropyl-N-((4'-methoxy-3'- methyl-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408944BDBM408944(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408947BDBM408947(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408940BDBM408940(Isopropyl 1-(N-((4′-methoxy-3′-methyl-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408941BDBM408941(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408942BDBM408942(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408943BDBM408943(Methyl 1-(2-cyclopentyl-N-((4'-methoxy-3'- methyl-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408935BDBM408935(Methyl 1-(trans-4-hydroxy-N-((4'-methoxy-3'- methy...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408936BDBM408936(Methyl 1-(trans-N- ((3'-chloro-4'-methoxy-[1,1'- b...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408939BDBM408939(Isopropyl 1-(N-((3'-cyano-4'-methoxy-[1,1'- biphen...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408964BDBM408964(Methyl 1-(N-((trans-4-(3- methoxyphenyl) cyclohexy...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408965BDBM408965(Methyl 1-(N-((trans-4-(4- methoxyphenyl) cyclohexy...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408967BDBM408967(Methyl 1-(N-((trans-4-(4-methoxy-3- methylphenyl) ...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408961BDBM408961(Methyl 1-(3,3-dimethyl-N-((trans-4-(m- tolyl)cyclo...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408962BDBM408962(Methyl 1-(3,3-dimethyl-N-((trans-4-(p- tolyl)cyclo...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408958BDBM408958(Isopropyl 1-(N-((trans-4-(4-methoxy-3-methylphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408959BDBM408959(Isopropyl 1-(N-((trans-4-(4-methoxy-3- methylpheny...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408952BDBM408952(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408953BDBM408953(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408968BDBM408968(Methyl 1-(N-((trans-4-(4-methoxy-3- methylphenyl) ...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408970BDBM408970(Methyl 1-(trans-4-hydroxy-N-((trans-4-(4- methoxy-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408882BDBM408882(Methyl 1-(N-((4'-(dimethylamino)-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408870BDBM408870((E)-Methyl 3-(2-(N-((4′-(dimethylamino)-[1,1...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408898BDBM408898(Methyl 1-(N- ((2',3'-difluoro-4'-methoxy- [1,1'-bi...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408899BDBM408899(Methyl 1-(N-((3'-cyano-4'-methyl-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408900BDBM408900(Methyl 1-(N-((3'-chloro-4'-cyano-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408894BDBM408894(Methyl 1-(N-((4'-methoxy-3'- methyl-[1,1'-biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408895BDBM408895(Methyl 1-(N-((2-cyano-4'-methoxy-3'- methyl- [1,1'...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408897BDBM408897(Methyl 1-(N-((4'-methoxy-3'-methyl- [1,1'-biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408890BDBM408890(Ethyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl]...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408891BDBM408891(Isopropyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphe...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408893BDBM408893(Methyl 1-(N-((3'-cyano-4'-methoxy-[1,1'- biphenyl]...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408887BDBM408887((E)-Methyl 3-(2-(N-((trans-4-(4-methoxy-3-methylph...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408888BDBM408888(Methyl 1-(N-((4′-methoxy-3′-methyl-[1,...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408889BDBM408889(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408915BDBM408915(Methyl 1-(N-((4'-methoxy-[1,1'-biphenyl]-4- yl)met...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408916BDBM408916(Methyl 1-(N-(4-(2,3-dihydrobenzofuran-5- yl)benzyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408917BDBM408917(Methyl 1-(N-(4-(2,3-dihydrobenzofuran-6- yl)benzyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408918BDBM408918(Methyl 1-(N-(4-(2,3- dihydrobenzo[b][1,4] dioxin-6...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408911BDBM408911(Methyl 1-(N-((3'-chloro-4'-(trifluoromethoxy)- [1,...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408912BDBM408912(Methyl 1-(N-((4'-cyano-3'-methyl-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408914BDBM408914(Methyl 1-(3,3-dimethyl-N-(4-(1-methyl-1H- indol-5-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408906BDBM408906(Methyl 1-(N-(4-(6-methoxy-5-methylpyridin-3- yl)be...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408908BDBM408908(Methyl 1-(N-(4-(6-(dimethylamino)pyridin-3- yl)ben...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408910BDBM408910(Methyl 1-(N-((4'-cyclopropyl-[1,1'-biphenyl]-4- yl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408903BDBM408903(Methyl 1-(N-(4-(2,2- difluorobenzo[d][1,3] dioxol-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408904BDBM408904(Methyl 1-(N-(4-(5-fluoro-6- methoxypyridin-3- yl)b...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408905BDBM408905(Methyl 1-(N-(4-(5-chloro-6- methoxypyridin-3- yl)b...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408931BDBM408931(Methyl 1-(N-((4'-(2-hydroxyethyl)-[1,1'- biphenyl]...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

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