Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 8632
TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409053BDBM409053(6-(5-Fluoro-6-methylpyridin-3-yl)-3,3-dimethyl-1-(...)
Affinity DataIC50: 27nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409054BDBM409054(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(5-(meth...)
Affinity DataIC50: 27nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409033BDBM409033(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(5-(meth...)
Affinity DataIC50: 32.1nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409050BDBM409050(1-(6-Cyclopropyl-5-(methylsulfonyl)pyridin-3-yl)-3...)
Affinity DataIC50: 38.5nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409044BDBM409044(1-(5-(Cyclopropylsulfonyl)pyridin-3-yl)-3,3-dimeth...)
Affinity DataIC50: 40nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409034BDBM409034(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(6-(meth...)
Affinity DataIC50: 40.1nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409037BDBM409037(5-(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-2-oxoin...)
Affinity DataIC50: 44.9nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409049BDBM409049(5-(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-2-oxoin...)
Affinity DataIC50: 71.7nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409048BDBM409048(5-(3,3-dimethyl-6-(2-methylpyrimidin-5-yl)-2-oxoin...)
Affinity DataIC50: 79.3nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409035BDBM409035(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(3-(meth...)
Affinity DataIC50: 106nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409046BDBM409046(5-(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-2-oxoin...)
Affinity DataIC50: 128nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409043BDBM409043(1-(5-(Isopropylsulfonyl)pyridin-3-yl)-3,3-dimethyl...)
Affinity DataIC50: 135nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409055BDBM409055(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(5-(meth...)
Affinity DataIC50: 157nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409047BDBM409047(1-(5-(Azetidin-1-ylsulfonyl)pyridin-3-yl)-3,3-dime...)
Affinity DataIC50: 169nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409031BDBM409031(1-(Benzo[b]thiophen-6-yl)-3,3-dimethyl-6-(2-methyl...)
Affinity DataIC50: 189nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409051BDBM409051(3,3-Dimethyl-6-(2-methyl-1-oxidopyrimidin-1-ium-5-...)
Affinity DataIC50: 218nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409045BDBM409045(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(5-(meth...)
Affinity DataIC50: 218nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409056BDBM409056(6'-(2-Methylpyrimidin-5-yl)-1'-(5-(methylsulfonyl)...)
Affinity DataIC50: 230nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409052BDBM409052(3,3-Dimethyl-6-(5-methylpyridin-3-yl)-1-(5-(methyl...)
Affinity DataIC50: 313nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetEquilibrative nucleoside transporter 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 409032BDBM409032(1-(Benzo[b]thiophen-4-yl)-3,3-dimethyl-6-(2-methyl...)
Affinity DataIC50: 844nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent