Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 8659
TargetTyrosine-protein kinase JAK1(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411421(US10385052, Example 2)
Affinity DataIC50: 0.350nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411423(US10385052, Example 4)
Affinity DataIC50: 0.410nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411424(US10385052, Example 5)
Affinity DataIC50: 0.590nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411425(US10385052, Example 6)
Affinity DataIC50: 0.680nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411426(US10385052, Example 7)
Affinity DataIC50: 0.740nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411420(US10385052, Example 1)
Affinity DataIC50: 0.990nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411421(US10385052, Example 2)
Affinity DataIC50: 1.5nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411425(US10385052, Example 6)
Affinity DataIC50: 1.60nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411422(US10385052, Example 3)
Affinity DataIC50: 1.70nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411423(US10385052, Example 4)
Affinity DataIC50: 1.90nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411426(US10385052, Example 7)
Affinity DataIC50: 2nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411424(US10385052, Example 5)
Affinity DataIC50: 2nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411425(US10385052, Example 6)
Affinity DataIC50: 2.5nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411424(US10385052, Example 5)
Affinity DataIC50: 2.70nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411421(US10385052, Example 2)
Affinity DataIC50: 2.90nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411420(US10385052, Example 1)
Affinity DataIC50: 4.60nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411422(US10385052, Example 3)
Affinity DataIC50: 5.10nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411426(US10385052, Example 7)
Affinity DataIC50: 5.10nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411423(US10385052, Example 4)
Affinity DataIC50: 7.10nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411422(US10385052, Example 3)
Affinity DataIC50: 10nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411424(US10385052, Example 5)
Affinity DataIC50: 10nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411426(US10385052, Example 7)
Affinity DataIC50: 11nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411420(US10385052, Example 1)
Affinity DataIC50: 15nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411422(US10385052, Example 3)
Affinity DataIC50: 18nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411425(US10385052, Example 6)
Affinity DataIC50: 19nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411420(US10385052, Example 1)
Affinity DataIC50: 22nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411421(US10385052, Example 2)
Affinity DataIC50: 26nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nissan Chemical

US Patent
LigandPNGBDBM411423(US10385052, Example 4)
Affinity DataIC50: 39nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent