Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 8660
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411440(US10385066, Example 17)
Affinity DataIC50: 0.300nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411430(US10385066, Example 2)
Affinity DataIC50: 0.5nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321161(US10174049, Example 28 | US9738658, Example 28 | U...)
Affinity DataIC50: 1.70nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411460(US10385066, Example 12)
Affinity DataIC50: 1.80nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411462(US10385066, Example 36)
Affinity DataIC50: 1.80nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321155(US10174049, Example 22 | US9796729, 22 | US1038506...)
Affinity DataIC50: 1.80nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321166(US10174049, Example 33 | US9738658, Example 33 | U...)
Affinity DataIC50: 2.5nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321141(US10174049, Example 8 | US9738658, Example 8 | US1...)
Affinity DataIC50: 2.90nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321140(US10174049, Example 7 | US9738658, Example 7 | US1...)
Affinity DataIC50: 3.20nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM351950(US9796729, 26 | US10385066, Example 26)
Affinity DataIC50: 3.40nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321153(US10174049, Example 20 | US9738658, Example 20 | U...)
Affinity DataIC50: 4.20nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321151(US10174049, Example 18 | US9738658, Example 18 | U...)
Affinity DataIC50: 4.80nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321163(US10174049, Example 30 | US9738658, Example 30 | U...)
Affinity DataIC50: 6.10nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321138(US10174049, Example 5 | US9738658, Example 5 | US1...)
Affinity DataIC50: 6.80nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411434(US10385066, Example 15)
Affinity DataIC50: 6.80nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321143(US10174049, Example 10 | US9738658, Example 10 | U...)
Affinity DataIC50: 7.90nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321162(US10174049, Example 29 | US9738658, Example 29 | U...)
Affinity DataIC50: 8.5nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321142(US10174049, Example 9 | US9738658, Example 9 | US1...)
Affinity DataIC50: 9.70nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411446(US10385066, Example 19)
Affinity DataIC50: 11.2nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321144(US10174049, Example 11 | US9738658, Example 11 | U...)
Affinity DataIC50: 13.3nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321147(US10174049, Example 14 | US9738658, Example 14 | U...)
Affinity DataIC50: 14.5nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411447(US10385066, Example 31)
Affinity DataIC50: 14.6nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321136(US10174049, Example 3 | US9738658, Example 3 | US1...)
Affinity DataIC50: 14.7nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321167(US10174049, Example 34 | US9738658, Example 34 | U...)
Affinity DataIC50: 15.8nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411458(US10385066, Example 23)
Affinity DataIC50: 16.1nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321154(US10174049, Example 21 | US9796729, 21 | US1038506...)
Affinity DataIC50: 16.3nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321151(US10174049, Example 18 | US9738658, Example 18 | U...)
Affinity DataIC50: 24.1nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321139(US10174049, Example 6 | US9738658, Example 6 | US9...)
Affinity DataIC50: 25nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411436(US10385066, Example 4)
Affinity DataIC50: 31.3nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321165(US10174049, Example 32 | US9738658, Example 32 | U...)
Affinity DataIC50: 38.1nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321134(US10174049, Example 1 | US9796729, 1 | US10385066,...)
Affinity DataIC50: 39.1nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411435(US10385066, Example 27)
Affinity DataIC50: 49.7nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411459(US10385066, Example 35)
Affinity DataIC50: 75nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411461(US10385066, Example 24)
Affinity DataIC50: 82.2nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321158(US10174049, Example 25 | US9738658, Example 25 | U...)
Affinity DataIC50: 93nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM321146(US10174049, Example 13 | US9796729, 13 | US1038506...)
Affinity DataIC50: 101nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent