Compile Data Set for Download or QSAR
Report error Found 279 Enz. Inhib. hit(s) with all data for entry = 8683
TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412836(US10399989, Example 49 | N-[[4-(4-amino-1-cyclohex...)
Affinity DataIC50: 0.400nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412883(US10399989, Example 23-isomer 2 | N-[[4-[4-amino-1...)
Affinity DataIC50: 0.400nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412838(US10399989, Example 51 | N-[[4-(4-amino-1-tert-but...)
Affinity DataIC50: 0.600nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412841(US10399989, Example 54 | N-[[4-[4-amino-1-[(1R,4R)...)
Affinity DataIC50: 0.700nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412788(US10399989, Example 4 | N-[[4-(4-amino-1-cyclopent...)
Affinity DataIC50: 0.800nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412828(US10399989, Example 41 | Ethyl 3-[4-amino-3-[4-[[(...)
Affinity DataIC50: 1.20nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412843(US10399989, Example 56 | N-[[4-[4-amino-1-[(1R)-in...)
Affinity DataIC50: 1.20nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412816(US10399989, Example 30 | N-[[4-[4-amino-1-[(1R,4R)...)
Affinity DataIC50: 1.40nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412826(US10399989, Example 39 | N-[[4-[4-amino-1-(4-metho...)
Affinity DataIC50: 1.40nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412824(US10399989, Example 37 | N-[[4-[4-amino-1-(3-hydro...)
Affinity DataIC50: 1.70nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412810(US10399989, Example 24 | N-[[4-[4-amino-1-[(1R*,3S...)
Affinity DataIC50: 2.20nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412853(US10399989, Example 66 | N-[[4-(4-amino-1-cyclopen...)
Affinity DataIC50: 4nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412843(US10399989, Example 56 | N-[[4-[4-amino-1-[(1R)-in...)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412843(US10399989, Example 56 | N-[[4-[4-amino-1-[(1R)-in...)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412840(US10399989, Example 53 | US10611766, Example 53)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412841(US10399989, Example 54 | N-[[4-[4-amino-1-[(1R,4R)...)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412841(US10399989, Example 54 | N-[[4-[4-amino-1-[(1R,4R)...)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412839(US10399989, Example 52 | US10611766, Example 52)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412839(US10399989, Example 52 | US10611766, Example 52)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412848(US10399989, Example 61 | US10611766, Example 61)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412849(US10399989, Example 62 | US10611766, Example 62)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412849(US10399989, Example 62 | US10611766, Example 62)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412847(US10399989, Example 60 | US10611766, Example 60)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412847(US10399989, Example 60 | US10611766, Example 60)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412848(US10399989, Example 61 | US10611766, Example 61)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412845(US10399989, Example 58 | US10611766, Example 58)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412845(US10399989, Example 58 | US10611766, Example 58)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412852(US10399989, Example 65 | US10611766, Example 65)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412853(US10399989, Example 66 | N-[[4-(4-amino-1-cyclopen...)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412853(US10399989, Example 66 | N-[[4-(4-amino-1-cyclopen...)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412852(US10399989, Example 65 | US10611766, Example 65)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412850(US10399989, Example 63 | US10611766, Example 63)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412850(US10399989, Example 63 | US10611766, Example 63)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412857(US10399989, Example 70 | US10611766, Example 70)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412857(US10399989, Example 70 | US10611766, Example 70)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412863(US10399989, Example 78 | US10399989, Example 76 | ...)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412866(US10399989, Example 79 | US10611766, Example 79)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412866(US10399989, Example 79 | US10611766, Example 79)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412864(US10399989, Example 77 | US10611766, Example 77)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412864(US10399989, Example 77 | US10611766, Example 77)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412863(US10399989, Example 78 | US10399989, Example 76 | ...)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412863(US10399989, Example 78 | US10399989, Example 76 | ...)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412863(US10399989, Example 78 | US10399989, Example 76 | ...)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412862(US10399989, Example 75 | US10611766, Example 75)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412862(US10399989, Example 75 | US10611766, Example 75)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412785(US10399989, Example 1 | US10611766, Example 1)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412880(US10399989, Example 93 | US10611766, Example 93)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412880(US10399989, Example 93 | US10611766, Example 93)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Loxo Oncology

US Patent
LigandPNGBDBM412878(US10399989, Example 91 | US10611766, Example 92)
Affinity DataIC50: 10nMAssay Description:BTKC481S binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Loxo Oncology

US Patent
LigandPNGBDBM412879(US10399989, Example 92)
Affinity DataIC50: 10nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

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