Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 8709
TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM153227(US8993756, 20-9 | US10421760, Comparative Example ...)
Affinity DataIC50: 0.0900nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413997(US10421760, Compound 7)
Affinity DataIC50: 0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414003(US10421760, Compound 14)
Affinity DataIC50: 0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413992(US10421760, Compound 1)
Affinity DataIC50: 0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413998(US10421760, Compound 8)
Affinity DataIC50: 0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413996(US10421760, Compound 5)
Affinity DataIC50: 0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414002(US10421760, Compound 13)
Affinity DataIC50: 0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413993(US10421760, Compound 2)
Affinity DataIC50: 0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413999(US10421760, Compound 9)
Affinity DataIC50: 0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413994(US10421760, Compound 3)
Affinity DataIC50: 0.300nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414004(US10421760, Compound 15)
Affinity DataIC50: 0.330nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414001(US10421760, Compound 12)
Affinity DataIC50: 0.350nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413995(US10421760, Compound 4)
Affinity DataIC50: 0.420nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414000(US10421760, Compound 10)
Affinity DataIC50: 0.680nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414005(US10421760, Compound 16)
Affinity DataIC50: 0.770nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414010(US10421760, Comparative Example 11(a) | US10421760...)
Affinity DataIC50: 19nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414010(US10421760, Comparative Example 11(a) | US10421760...)
Affinity DataIC50: 21nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414008(US10421760, Comparative Example 8)
Affinity DataIC50: 21.4nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414007(US10421760, Comparative Example 2)
Affinity DataIC50: 27nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414006(US10421760, Comparative Example 1)
Affinity DataIC50: 44nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414009(US10421760, Comparative Example 10)
Affinity DataIC50: 125nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414009(US10421760, Comparative Example 10)
Affinity DataIC50: 166nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413997(US10421760, Compound 7)
Affinity DataIC50: 330nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414009(US10421760, Comparative Example 10)
Affinity DataIC50: 414nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413998(US10421760, Compound 8)
Affinity DataIC50: 430nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413996(US10421760, Compound 5)
Affinity DataIC50: 430nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413997(US10421760, Compound 7)
Affinity DataIC50: 440nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414004(US10421760, Compound 15)
Affinity DataIC50: 450nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413992(US10421760, Compound 1)
Affinity DataIC50: 470nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413993(US10421760, Compound 2)
Affinity DataIC50: 480nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414002(US10421760, Compound 13)
Affinity DataIC50: 490nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414007(US10421760, Comparative Example 2)
Affinity DataIC50: 600nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414000(US10421760, Compound 10)
Affinity DataIC50: 660nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413996(US10421760, Compound 5)
Affinity DataIC50: 720nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414007(US10421760, Comparative Example 2)
Affinity DataIC50: 730nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413994(US10421760, Compound 3)
Affinity DataIC50: 850nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414001(US10421760, Compound 12)
Affinity DataIC50: 870nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413992(US10421760, Compound 1)
Affinity DataIC50: 880nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414006(US10421760, Comparative Example 1)
Affinity DataIC50: 880nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413999(US10421760, Compound 9)
Affinity DataIC50: 880nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414010(US10421760, Comparative Example 11(a) | US10421760...)
Affinity DataIC50: 880nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413993(US10421760, Compound 2)
Affinity DataIC50: 900nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM153227(US8993756, 20-9 | US10421760, Comparative Example ...)
Affinity DataIC50: 1.00E+3nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM153227(US8993756, 20-9 | US10421760, Comparative Example ...)
Affinity DataIC50: 1.00E+3nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414005(US10421760, Compound 16)
Affinity DataIC50: 1.00E+3nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414006(US10421760, Comparative Example 1)
Affinity DataIC50: 1.10E+3nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414003(US10421760, Compound 14)
Affinity DataIC50: 1.20E+3nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413995(US10421760, Compound 4)
Affinity DataIC50: 1.30E+3nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413998(US10421760, Compound 8)
Affinity DataIC50: 1.40E+3nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM413994(US10421760, Compound 3)
Affinity DataIC50: 1.50E+3nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

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