Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 8780
TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419309BDBM419309(2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)tr...)
Affinity DataKi:  1nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419306BDBM419306(3-[2-[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1...)
Affinity DataKi:  5nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419278BDBM419278(2-{[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3...)
Affinity DataKi:  6nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419300BDBM419300(2-[2-[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1...)
Affinity DataKi:  6nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419296BDBM419296(2-[[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-y...)
Affinity DataKi:  9nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419273BDBM419273((2-{[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-...)
Affinity DataKi:  11nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419272BDBM419272(2-[[5-tert-Butyl-7-[(3S)-3-hydroxypyrrolidin-1-yl]...)
Affinity DataKi:  16nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419302BDBM419302(2-[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl...)
Affinity DataKi:  27nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419304BDBM419304(2-[2-[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1...)
Affinity DataKi:  63nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419303BDBM419303(5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[[2...)
Affinity DataKi:  72nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419279BDBM419279(1-{5-tert-Butyl-3-[(2-chlorophenyl)methyl]-3H-[1,2...)
Affinity DataKi:  85nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419275BDBM419275(5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-{[2...)
Affinity DataKi:  88nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419276BDBM419276((3S)-1-(5-tert-Butyl-3-{[2-(isothiocyanatomethyl)p...)
Affinity DataKi:  91nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419307BDBM419307(2-[[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-y...)
Affinity DataKi:  95nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419306BDBM419306(3-[2-[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1...)
Affinity DataKi:  135nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419285BDBM419285(7-(3-Azidopyrrolidin-1-yl)-5-tert-butyl-3-[(4-meth...)
Affinity DataKi:  137nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419299BDBM419299(2-[2-[2-[[5-[Difluoro(phenyl)methyl]-7-(3,3-difluo...)
Affinity DataKi:  138nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419281BDBM419281((3S)-1-{5-tert-Butyl-3-[(4-methyl-1,2,5-oxadiazol-...)
Affinity DataKi:  153nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419305BDBM419305(2-[2-[2-[[5-[Difluoro(phenyl)methyl]-7-(3,3-difluo...)
Affinity DataKi:  177nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419300BDBM419300(2-[2-[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1...)
Affinity DataKi:  205nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419288BDBM419288(7-(3-Azidopyrrolidin-1-yl)-5-tert-butyl-3-[(2-chlo...)
Affinity DataKi:  210nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419296BDBM419296(2-[[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-y...)
Affinity DataKi:  211nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419305BDBM419305(2-[2-[2-[[5-[Difluoro(phenyl)methyl]-7-(3,3-difluo...)
Affinity DataKi:  230nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419301BDBM419301(3-[[2-[2-(Benzotriazol-1-ylsulfonyl)ethyl]phenyl]m...)
Affinity DataKi:  246nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419298BDBM419298(5-[Difluoro(phenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataKi:  262nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419274BDBM419274([2-({5-tert-Butyl-7-[(3S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataKi:  283nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419277BDBM419277(5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(2...)
Affinity DataKi:  300nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419309BDBM419309(2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)tr...)
Affinity DataKi:  311nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419280BDBM419280(1-{5-tert-Butyl-3-[(2-chlorophenyl)methyl]-3H-[1,2...)
Affinity DataKi:  383nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419287BDBM419287(5-tert-Butyl-7-(3-isothiocyanatopyrrolidin-1-yl)-3...)
Affinity DataKi:  426nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419308BDBM419308(5-tert-butyl-7-(3,3-Difluoropyrrolidin-1-yl)-3-[[2...)
Affinity DataKi:  541nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419307BDBM419307(2-[[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-y...)
Affinity DataKi:  560nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419304BDBM419304(2-[2-[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1...)
Affinity DataKi:  588nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419297BDBM419297(2-[[5-[Difluoro(phenyl)methyl]-7-(3,3-difluoropyrr...)
Affinity DataKi:  630nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419282BDBM419282((3R)-1-{5-tert-Butyl-3-[(4-methyl-1,2,5-oxadiazol-...)
Affinity DataKi:  640nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419292BDBM419292(7-(3-Azidopyrrolidin-1-yl)-3-[(2-chlorophenyl)meth...)
Affinity DataKi:  729nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419278BDBM419278(2-{[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3...)
Affinity DataKi:  931nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419289BDBM419289(5-[Difluoro(phenyl)methyl]-7-[3-(methyldisulfanyl)...)
Affinity DataKi:  1.03E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419299BDBM419299(2-[2-[2-[[5-[Difluoro(phenyl)methyl]-7-(3,3-difluo...)
Affinity DataKi:  1.08E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419295BDBM419295(2-[[5-[Difluoro(phenyl)methyl]-7-[(3S)-3-hydroxypy...)
Affinity DataKi:  1.13E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419293BDBM419293(3-[(2-Chlorophenyl)methyl]-5-[difluoro(phenyl)meth...)
Affinity DataKi:  1.24E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419291BDBM419291(7-(3-Azidopyrrolidin-1-yl)-5-[difluoro(phenyl)meth...)
Affinity DataKi:  1.30E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419302BDBM419302(2-[2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl...)
Affinity DataKi:  1.36E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419286BDBM419286(5-tert-Butyl-3-[(2-chlorophenyl)methyl]-7-(3-isoth...)
Affinity DataKi:  1.36E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419290BDBM419290(3-[(2-Chlorophenyl)methyl]-5-[difluoro(phenyl)meth...)
Affinity DataKi:  1.37E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419294BDBM419294(5-[Difluoro(phenyl)methyl]-7-(3-isothiocyanatopyrr...)
Affinity DataKi:  1.45E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419294BDBM419294(5-[Difluoro(phenyl)methyl]-7-(3-isothiocyanatopyrr...)
Affinity DataKi:  1.46E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419279BDBM419279(1-{5-tert-Butyl-3-[(2-chlorophenyl)methyl]-3H-[1,2...)
Affinity DataKi:  1.47E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419284BDBM419284((3R)-1-{5-tert-Butyl-3-[(2-chlorophenyl)methyl]-3H...)
Affinity DataKi:  1.56E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 419303BDBM419303(5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[[2...)
Affinity DataKi:  1.86E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

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