Compile Data Set for Download or QSAR
Report error Found 153 Enz. Inhib. hit(s) with all data for entry = 8934
TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430158(4-(2-fluoro-4-methoxyphenyl)-5-((2-methylpyridin-4...)
Affinity DataIC50: 29nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430113(4-(2-fluoro-4-methoxyphenyl)-5-(pyridin-3-ylmethox...)
Affinity DataIC50: 39nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430126(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataIC50: 66nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430220(5-((2-cyanobenzyl)oxy)-4-(4-fluorophenyl)picolinam...)
Affinity DataIC50: 98nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430124(4-(4-fluorophenyl)-5-(imidazo[1,2-a]pyridin-6-ylme...)
Affinity DataIC50: 129nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430119(4-(4-fluorophenyl)-5-((2-methylpyridin-4-yl)methox...)
Affinity DataIC50: 195nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430120(4-(4-fluorophenyl)-5-((2-methoxypyridin-4-yl)metho...)
Affinity DataIC50: 204nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430153(4-(2-fluoro-4-methoxyphenyl)-5-((6- methylpyridin-...)
Affinity DataIC50: 216nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430118(4-(4-fluorophenyl)-5-(pyridin-4-ylmethoxy)picolina...)
Affinity DataIC50: 239nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430186(4-(4-fluorophenyl)-5-(2-((2-(trifluoromethyl)pyrid...)
Affinity DataIC50: 242nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430219(5-((3-cyano-2-fluorobenzyl)oxy)-4-(4-fluorophenyl)...)
Affinity DataIC50: 254nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430125(4-(4-fluorophenyl)-5-( thiazol-5-ylmethoxy)picolin...)
Affinity DataIC50: 263nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430116(4-(4-fluorophenyl)-5-((6-methoxypyridin-3-yl)metho...)
Affinity DataIC50: 266nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430217(5-((5-cyano-2-fluorobenzyl)oxy)-4-(4-fluorophenyl)...)
Affinity DataIC50: 313nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430115(4-(4-fluorophenyl)-5-((6-methylpyridin-3-yl)methox...)
Affinity DataIC50: 343nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430105(5-((3,5-difluorobenzyl)oxy)-4-(2-fluoro-4-methoxyp...)
Affinity DataIC50: 395nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430104(5-((3,5-difluorobenzyl)oxy)-4-(4-fluorophenyl)pico...)
Affinity DataIC50: 401nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430188(4-(4-fluorophenyl)-5-(2-((2-methylpyridin-4-yl)oxy...)
Affinity DataIC50: 410nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430215(5-((3-Cyanobenzyl)oxy)-4-(4-fluorophenyl)picolinam...)
Affinity DataIC50: 429nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430082(US10538491, Compound 8 | 5-((6-chloropyridin-3-yl)...)
Affinity DataIC50: 429nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430156(4-(2-fluoro-4-methoxyphenyl)-5-((6-(trifluoromethy...)
Affinity DataIC50: 440nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430163(4-(4-fluorophenyl)-5-(((2-(trifluoromethyl)pyridin...)
Affinity DataIC50: 477nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430190(4-(4-fluorophenyl)-5-((1-((2-(trifluoromethyl)pyri...)
Affinity DataIC50: 483nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430183(4-(4-fluorophenyl)-5-(2-((6-fluoropyridin-3-yl)oxy...)
Affinity DataIC50: 502nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430122(4-(4-fluorophenyl)-5-(1-(pyridin-4-yl)ethoxy)picol...)
Affinity DataIC50: 504nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430112(4-(4-fluorophenyl)-5-(pyridin-3-ylmethoxy)picolina...)
Affinity DataIC50: 507nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430225(5-(2-(3-cyano-2-fluorophenoxy)ethoxy)-4-(4-fluorop...)
Affinity DataIC50: 528nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430148(5-((2,2-dimethylmorpholino)methyl)-4-(4-fluorophen...)
Affinity DataIC50: 531nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430187(4-(4-fluorophenyl)-5-(2-((2-fluoropyridin-4-yl)oxy...)
Affinity DataIC50: 615nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430181(5-(2-((5-bromopyridin-3-yl)oxy)ethoxy)-4-(4-fluoro...)
Affinity DataIC50: 624nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430161(4-(4-fluorophenyl)-5-(((6-(trifluoromethyl)pyridin...)
Affinity DataIC50: 639nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430110(5-((5-bromo-2-fluorobenzyl)oxy)-4-(4-fluorophenyl)...)
Affinity DataIC50: 650nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430221(5-((5-cyanopyridin-3-yOmethoxy)-4-(4-fluorophenyl)...)
Affinity DataIC50: 683nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430227(5-(2-((5-cyanopyridin-3-yl)oxy)ethoxy)-4-(4-fluoro...)
Affinity DataIC50: 691nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430117(4-(4-fluorophenyl)-5-((6-(trifluoromethyl)pyridin-...)
Affinity DataIC50: 717nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430184(4-(4-fluorophenyl)-5-(2-((6-methylpyridin-3-yl)oxy...)
Affinity DataIC50: 738nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430182(4-(4-fluorophenyl)-5-(2-((5-fluoropyridin-3-yl)oxy...)
Affinity DataIC50: 827nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430194(4-(4-fluorophenyl)-5-(2-((2-(trifluoromethyl)pyrid...)
Affinity DataIC50: 835nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430216(5-((3-cyano-5-fluorobenzyl)oxy)-4-(4-fluorophenyl)...)
Affinity DataIC50: 944nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430149(5-(((cis)-2,6-dimethylmorpholino)methyl)-4-(4-fluo...)
Affinity DataIC50: 987nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430127(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-4-yl)me...)
Affinity DataIC50: 1.00E+3nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430202(4-(4-fluorophenyl)-5-(((tetrahydro-2H-pyran-4-yl)m...)
Affinity DataIC50: 1.05E+3nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430109(5-((2-bromobenzyl)oxy)-4-(4-fluorophenyl)picolinam...)
Affinity DataIC50: 1.11E+3nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430222(5-(2-(3-cyanophenoxy)ethoxy)-4-(4-fluorophenyl)pic...)
Affinity DataIC50: 1.22E+3nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430212(4-(4-fluorophenyl)-5-(3-((6-methylpyridin-3-yl)oxy...)
Affinity DataIC50: 1.28E+3nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430185(4-(4-fluorophenyl)-5-(2-((6-(trifluoromethyl)pyrid...)
Affinity DataIC50: 1.31E+3nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430223(5-(2-(3-cyano-5-fluorophenoxy)ethoxy)-4-(4-fluorop...)
Affinity DataIC50: 1.37E+3nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430128(4-(4-fluorophenyl)-5-(2-(pyridin-3-yloxy)ethoxy)pi...)
Affinity DataIC50: 1.37E+3nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430224(5-(2-(3-cyano-4-fluorophenoxy)ethoxy)-4-(4-fluorop...)
Affinity DataIC50: 1.39E+3nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM430111(5-((3-bromo-5-fluorobenzyl)oxy)-4-(4-fluorophenyl)...)
Affinity DataIC50: 1.47E+3nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

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