Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 8895
TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426672(US10544095, Example 120)
Affinity DataIC50: 120nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426656(US10544095, Example 79)
Affinity DataIC50: 120nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426655(US10544095, Example 77)
Affinity DataIC50: 170nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426649(US10544095, Example 35)
Affinity DataIC50: 420nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426654(US10544095, Example 76)
Affinity DataIC50: 470nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426648(US10544095, Example 34)
Affinity DataIC50: 520nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426653(US10544095, Example 58)
Affinity DataIC50: 530nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426663(US10544095, Example 93)
Affinity DataIC50: 550nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426647(US10544095, Example 32)
Affinity DataIC50: 730nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426646(US10544095, Example 26)
Affinity DataIC50: 730nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426645(US10544095, Example 21)
Affinity DataIC50: 740nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426650(US10544095, Example 36)
Affinity DataIC50: 770nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426668(US10544095, Example 97)
Affinity DataIC50: 820nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426664(US10544095, Example 94)
Affinity DataIC50: 840nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426671(US10544095, Example 101)
Affinity DataIC50: 840nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426641(US10544095, Example 8)
Affinity DataIC50: 890nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426657(US10544095, Example 80)
Affinity DataIC50: 900nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426669(US10544095, Example 98)
Affinity DataIC50: 910nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426651(US10544095, Example 40)
Affinity DataIC50: 930nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426660(US10544095, Example 87)
Affinity DataIC50: 930nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426661(US10544095, Example 88)
Affinity DataIC50: 940nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426652(US10544095, Example 50)
Affinity DataIC50: 960nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426667(US10544095, Example 96)
Affinity DataIC50: 1.00E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426639(US10544095, Example 6)
Affinity DataIC50: 1.00E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426633(US10544095, Example 2)
Affinity DataIC50: 1.10E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426670(US10544095, Example 99)
Affinity DataIC50: 1.10E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426644(US10544095, Example 18)
Affinity DataIC50: 1.10E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426665(US10544095, Example 95)
Affinity DataIC50: 1.30E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426659(US10544095, Example 86)
Affinity DataIC50: 1.30E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426632(US10544095, Example 1)
Affinity DataIC50: 1.50E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426642(US10544095, Example 9)
Affinity DataIC50: 1.80E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426658(US10544095, Example 84)
Affinity DataIC50: 1.90E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426662(US10544095, Example 90)
Affinity DataIC50: 2.00E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426637(US10544095, Example 4)
Affinity DataIC50: 2.10E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426636(US10544095, Example 3)
Affinity DataIC50: 2.10E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426643(US10544095, Example 10)
Affinity DataIC50: 2.40E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426640(US10544095, Example 7)
Affinity DataIC50: 4.40E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM426638(US10544095, Example 5)
Affinity DataIC50: 4.70E+3nMAssay Description:To measure the TDO2 activity, the procedure described in Dolusic et al. J. Med. Chem.; 2011, 54, 5320-533 was adapted: the reaction mixture contained...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent