Compile Data Set for Download or QSAR
Report error Found 75 Enz. Inhib. hit(s) with all data for entry = 8940
TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430334BDBM430334(2-fluoro-N-[3-(1-hydroxy-1-methylethyl)- 7-phenyli...)
Affinity DataIC50: 0.200nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430343BDBM430343((R) or (S)-2-fluoro-N-[3-(1- hydroxyethyl)-7-pheny...)
Affinity DataIC50: 0.310nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430357BDBM430357(2-fluoro-N-[3- (hydroxymethyl)-6- phenylpyrazolo[1...)
Affinity DataIC50: 0.330nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430354BDBM430354(US10556900, Compound 36)
Affinity DataIC50: 0.400nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430340BDBM430340(8-({[2-fluoro-5-(1-methyl-1H-pyrazol-3- yl)-4- (tr...)
Affinity DataIC50: 0.510nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430341BDBM430341(2-fluoro-N-[3-(hydroxymethyl)-7- phenylimidazo[1,2...)
Affinity DataIC50: 0.520nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430360BDBM430360(US10556900, Compound 42)
Affinity DataIC50: 0.660nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430347BDBM430347(US10556900, Compound 30 | (R) or (S)-2-fluoro-N-[3...)
Affinity DataIC50: 0.740nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430343BDBM430343((R) or (S)-2-fluoro-N-[3-(1- hydroxyethyl)-7-pheny...)
Affinity DataIC50: 0.810nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430367BDBM430367(US10556900, Compound 48)
Affinity DataIC50: 0.900nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430349BDBM430349(2-fluoro-N-[3-(1-hydroxy-1-methylethyl)- 7-phenyli...)
Affinity DataIC50: 0.940nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430328BDBM430328(US10556900, Compound 10)
Affinity DataIC50: 1.10nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430335BDBM430335(2-chloro-N-[3-(1-hydroxy-1- methylethyl)-7-phenyli...)
Affinity DataIC50: 1.10nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430387BDBM430387(US10556900, Compound 70)
Affinity DataIC50: 1.20nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430358BDBM430358(N-[3-(hydroxymethyl)-6- phenylpyrazolo[1,5- a]pyri...)
Affinity DataIC50: 1.40nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430347BDBM430347(US10556900, Compound 30 | (R) or (S)-2-fluoro-N-[3...)
Affinity DataIC50: 1.70nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430345BDBM430345((R) or (S)-2-fluoro-N-[3-(1- hydroxyethyl)-7-pheny...)
Affinity DataIC50: 1.80nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430356BDBM430356(2-fluoro-N-[3-(1-hydroxy- 1-methylethyl)-6- phenyl...)
Affinity DataIC50: 1.80nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430337BDBM430337(2-fluoro-N-[3-(1-hydroxy-1-methylethyl)- 7-phenyli...)
Affinity DataIC50: 1.90nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430392BDBM430392(US10556900, Compound 75)
Affinity DataIC50: 2nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430393BDBM430393(US10556900, Compound 49)
Affinity DataIC50: 2nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430359BDBM430359(2-fluoro-N-[3- (hydroxymethyl)-6- phenylpyrazolo[1...)
Affinity DataIC50: 2.10nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430325BDBM430325(US10556900, Compound 7)
Affinity DataIC50: 2.10nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430332BDBM430332((R) or (S)-N-[3-(1-hydroxyethyl)-7- phenylimidazo[...)
Affinity DataIC50: 2.20nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430331BDBM430331(N-[3-(hydroxymethyl)-7- phenylimidazo[1,2-a]pyridi...)
Affinity DataIC50: 2.40nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430342BDBM430342(2-fluoro-N-[3-(hydroxymethyl)-7- phenylimidazo[1,2...)
Affinity DataIC50: 2.5nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430365BDBM430365(US10556900, Compound 46)
Affinity DataIC50: 2.90nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430327BDBM430327(US10556900, Compound 9)
Affinity DataIC50: 3.30nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430345BDBM430345((R) or (S)-2-fluoro-N-[3-(1- hydroxyethyl)-7-pheny...)
Affinity DataIC50: 3.5nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430339BDBM430339(8-({[2-fluoro-5-pyridin-2-yl-4- (trifluoromethyl)p...)
Affinity DataIC50: 3.70nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430329BDBM430329(US10556900, Compound 11)
Affinity DataIC50: 4nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430378BDBM430378(US10556900, Compound 61)
Affinity DataIC50: 4nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430391BDBM430391(US10556900, Compound 74)
Affinity DataIC50: 4.20nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430363BDBM430363(US10556900, Compound 45)
Affinity DataIC50: 4.30nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430382BDBM430382(US10556900, Compound 65)
Affinity DataIC50: 4.40nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430353BDBM430353(US10556900, Compound 35)
Affinity DataIC50: 4.40nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430355BDBM430355(N-[3-(1-hydroxy-1- methylethyl)-6- phenylpyrazolo[...)
Affinity DataIC50: 4.5nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430366BDBM430366(US10556900, Compound 47)
Affinity DataIC50: 4.5nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430390BDBM430390(US10556900, Compound 73)
Affinity DataIC50: 4.80nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430370BDBM430370(US10556900, Compound 52)
Affinity DataIC50: 4.90nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430361BDBM430361(US10556900, Compound 43)
Affinity DataIC50: 5nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430389BDBM430389(US10556900, Compound 72)
Affinity DataIC50: 5.10nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430332BDBM430332((R) or (S)-N-[3-(1-hydroxyethyl)-7- phenylimidazo[...)
Affinity DataIC50: 5.10nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430381BDBM430381(US10556900, Compound 64)
Affinity DataIC50: 5.5nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430330BDBM430330(8-({[3-(1-methyl-1H-pyrazol-3-yl)-4- (trifluoromet...)
Affinity DataIC50: 5.70nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430326BDBM430326(US10556900, Compound 8)
Affinity DataIC50: 6.20nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430350BDBM430350(N-[3-(1-hydroxy-1-methylethyl)-7- phenylimidazo[1,...)
Affinity DataIC50: 6.20nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430351BDBM430351(3-(1-methyl-1H-pyrazol-3-yl)-N-(7- phenyl[1,2,4]tr...)
Affinity DataIC50: 6.30nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430386BDBM430386(US10556900, Compound 69)
Affinity DataIC50: 6.5nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 430388BDBM430388(US10556900, Compound 71)
Affinity DataIC50: 6.60nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
US Patent

Displayed 1 to 50 (of 75 total ) | Next | Last >>
Jump to: