Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 8970
TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433346BDBM433346(US10561657, Example 27)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433345BDBM433345(US10561657, Example 26)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433348BDBM433348(US10561657, Example 28)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433342BDBM433342(US10561657, Example 19)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433344BDBM433344(US10561657, Example 25)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433343BDBM433343(US10561657, Example 24)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433338BDBM433338(US10561657, Example 15)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433336BDBM433336(US10561657, Example 14)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433340BDBM433340(US10561657, Example 17)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433332BDBM433332(US10561657, Example 11)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433331BDBM433331(US10561657, Example 10)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433335BDBM433335(US10561657, Example 13)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433333BDBM433333(US10561657, Example 12)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433329BDBM433329(US10561657, Example 7)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433328BDBM433328(US10561657, Example 6)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433330BDBM433330(US10561657, Example 9)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [V617F](Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433329BDBM433329(US10561657, Example 7)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [V617F](Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433324BDBM433324(US10561657, Example 1)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433327BDBM433327(US10561657, Example 5)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433326BDBM433326(US10561657, Example 3)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433323BDBM433323(US10561657, Ruxolitinib | US10617692, Ruxolitinib ...)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433324BDBM433324(US10561657, Example 1)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [V617F](Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433323BDBM433323(US10561657, Ruxolitinib | US10617692, Ruxolitinib ...)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433325BDBM433325(US10561657, Example 2)
Affinity DataIC50: 100nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433339BDBM433339(US10561657, Example 16)
Affinity DataIC50: 100nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandChemical structure of BindingDB Monomer ID 433341BDBM433341(US10561657, Example 18)
Affinity DataIC50: 1.00E+3nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent