Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 9017
TargetCyclin-dependent kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435712(US10570141, Example 1)
Affinity DataIC50: 0.800nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435716(US10570141, Example 5)
Affinity DataIC50: 1.46nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435713(US10570141, Example 2)
Affinity DataIC50: 2.12nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM148264(US8962630, 74 | Ribociclib | LEE011 | Kisqali | 7-...)
Affinity DataIC50: 2.14nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435717(US10570141, Example 6)
Affinity DataIC50: 2.37nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435715(US10570141, Example 4)
Affinity DataIC50: 2.57nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435714(US10570141, Example 3)
Affinity DataIC50: 3.40nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435712(US10570141, Example 1)
Affinity DataIC50: 5.70nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435716(US10570141, Example 5)
Affinity DataIC50: 9.85nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435715(US10570141, Example 4)
Affinity DataIC50: 11.1nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435714(US10570141, Example 3)
Affinity DataIC50: 18.7nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435713(US10570141, Example 2)
Affinity DataIC50: 21nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM148264(US8962630, 74 | Ribociclib | LEE011 | Kisqali | 7-...)
Affinity DataIC50: 26.9nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435717(US10570141, Example 6)
Affinity DataIC50: 30.6nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent