Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 9052
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437726BDBM437726(US10597382, Example 6)
Affinity DataIC50: 5.5nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437710BDBM437710(US10597382, Example 1)
Affinity DataIC50: 5.5nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437775BDBM437775(US10597382, Example 14)
Affinity DataIC50: 5.5nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437770BDBM437770(US10597382, Example 13)
Affinity DataIC50: 5.5nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437749BDBM437749(US10597382, Example 10)
Affinity DataIC50: 55nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437737BDBM437737(US10597382, Example 9)
Affinity DataIC50: 55nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437728BDBM437728(US10597382, Example 7)
Affinity DataIC50: 55nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437711BDBM437711(US10597382, Example 2)
Affinity DataIC50: 55nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437720BDBM437720(US10597382, Example 4 | US10597382, Example 3)
Affinity DataIC50: 55nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437779BDBM437779(US10597382, Example 16)
Affinity DataIC50: 55nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437778BDBM437778(US10597382, Example 15)
Affinity DataIC50: 55nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437759BDBM437759(US10597382, Example 12)
Affinity DataIC50: 550nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437756BDBM437756(US10597382, Example 11)
Affinity DataIC50: 550nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437729BDBM437729(US10597382, Example 8)
Affinity DataIC50: 550nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437720BDBM437720(US10597382, Example 4 | US10597382, Example 3)
Affinity DataIC50: 550nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 437722BDBM437722(US10597382, Example 5)
Affinity DataIC50: 1.00E+3nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent