Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 9053
LigandChemical structure of BindingDB Monomer ID 437915BDBM437915((2S)-3-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[5-fl...)
Affinity DataIC50: 1.08nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437925BDBM437925((2S)-3-(4- fluorophenyl)sulfonyl-N-[[2- (trifluoro...)
Affinity DataIC50: 1.18nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437848BDBM437848((2S)-N-[[5-chloro-2-[2- (trifluoromethyl)pyrimidin...)
Affinity DataIC50: 1.55nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437932BDBM437932((2S)-3-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[5- (...)
Affinity DataIC50: 1.85nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437842BDBM437842((2S)-N-[[2-cyclopropyl-6-[2- (trifluoromethyl)pyri...)
Affinity DataIC50: 2.15nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437894BDBM437894((2S)-3-(4- fluorophenyl)sulfonyl-N-[[5- (trifluoro...)
Affinity DataIC50: 2.61nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437854BDBM437854((2S)-3-(4- fluorophenyl)sulfonyl-N-[[5- (trifluoro...)
Affinity DataIC50: 2.77nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437955BDBM437955((2S)-N-[[2-cyclopropyl-6-[2- (trifluoromethyl)pyri...)
Affinity DataIC50: 3.55nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437851BDBM437851((2S)-N-[[5-bromo-2-[2- (trifluoromethyl)pyrimidin-...)
Affinity DataIC50: 3.82nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437976BDBM437976((2S)-3-(4- fluorophenyl)sulfonyl-N-[[2- (2,2,2-tri...)
Affinity DataIC50: 4.24nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437802BDBM437802((2S)-N-[[2-chloro-6-[2- (trifluoromethyl)pyrimidin...)
Affinity DataIC50: 4.64nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437920BDBM437920((2S)-3-(4- fluorophenyl)sulfonyl-N-[[3- (trifluoro...)
Affinity DataIC50: 4.84nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437862BDBM437862((2S)-3-(4- fluorophenyl)sulfonyl-N-[[2- fluoro-5-[...)
Affinity DataIC50: 6.06nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437845BDBM437845((2S)-N-[[5-chloro-4-[2- (trifluoromethyl)pyrimidin...)
Affinity DataIC50: 6.08nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437886BDBM437886((2S)-3-(4- fluorophenyl)sulfonyl-N-[[3- fluoro-5-[...)
Affinity DataIC50: 6.11nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437935BDBM437935((2S)-N-[[6-cyclopropyl-4-[2- (trifluoromethyl)pyri...)
Affinity DataIC50: 7.24nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437885BDBM437885((2S)-3-(4- fluorophenyl)sulfonyl-N-[[3- fluoro-5-[...)
Affinity DataIC50: 8.97nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437908BDBM437908((2S)-N-[[5-(difluoromethyl)-2- [2-(trifluoromethyl...)
Affinity DataIC50: 9.01nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437855BDBM437855((2S)-3-(4- fluorophenyl)sulfonyl-N-[[2- fluoro-5-[...)
Affinity DataIC50: 9.89nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437896BDBM437896((2S)-N-[[5-(difluoromethyl)-2- [2-(trifluoromethyl...)
Affinity DataIC50: 9.92nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437913BDBM437913((2S)-3-(3,4- difluorophenyl)sulfonyl-N-[[5- fluoro...)
Affinity DataIC50: 10.6nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437790BDBM437790((2S)-3-(4- fluorophenyl)sulfonyl-N- [[5-fluoro-2-[...)
Affinity DataIC50: 11.3nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437917BDBM437917((2S)-3-(4- fluorophenyl)sulfonyl-N-[[2- (trifluoro...)
Affinity DataIC50: 12.1nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437881BDBM437881((2S)-N-[[2-fluoro-5-[2-methyl- 5-(trifluoromethyl)...)
Affinity DataIC50: 15.7nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437837BDBM437837((2S)-N-[[5-cyano-2-[2- (trifluoromethyl)pyrimidin-...)
Affinity DataIC50: 16nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437892BDBM437892((2S)-N-[[5-cyclopropyl-2-[2- (trifluoromethyl)pyri...)
Affinity DataIC50: 16.3nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437816BDBM437816((2S)-3-(4- fluorophenyl)sulfonyl-N-[[5- fluoro-4-[...)
Affinity DataIC50: 16.8nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437840BDBM437840((2S)-N-[[2-cyano-5-[2- (trifluoromethyl)pyrimidin-...)
Affinity DataIC50: 17.1nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437959BDBM437959((2S)-3-(4- fluorophenyl)sulfonyl-N-[[3- methoxy-1-...)
Affinity DataIC50: 19.1nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437817BDBM437817((2S)-N-[[5-chloro-4-[2- (trifluoromethyl)pyrimidin...)
Affinity DataIC50: 20.8nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437794BDBM437794((2S)-3-(4- fluorophenyl)sulfonyl-N-[[6- [6-(triflu...)
Affinity DataIC50: 24.8nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437888BDBM437888((2S)-N-[[3-fluoro-5-[2-methyl- 5-(trifluoromethyl)...)
Affinity DataIC50: 27.6nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437801BDBM437801((2S)-3-(4- fluorophenyl)sulfonyl-N-[[2- [2-(triflu...)
Affinity DataIC50: 36.4nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437782BDBM437782((2S)-3-(4- fluorophenyl)sulfonyl-N- [[6-[2- (trifl...)
Affinity DataIC50: 42.9nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 437847BDBM437847((2S)-3-(4- fluorophenyl)sulfonyl-N-[[5- fluoro-4-[...)
Affinity DataIC50: 90.2nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent