Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 9068
TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230876BDBM230876(US10045974, 12 | US9346797, 12 | US10603310, Compo...)
Affinity DataKi:  6.10nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230869BDBM230869(US10045974, 13 | US9346797, 13 | US9346797, 5 | US...)
Affinity DataKi:  6.70nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 228168BDBM228168(US10045974, 9 | (S)-N-(3-(6-amino-2-(difluoromethy...)
Affinity DataKi:  6.90nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230871BDBM230871(US10045974, 7 | US9346797, 7 | US10603310, Compoun...)
Affinity DataKi:  7.40nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 228170BDBM228170(BDBM230875 | US10045974, 11 | (S)-N-(3-(6-amino-2-...)
Affinity DataKi:  7.80nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230867BDBM230867(US10045974, 14 | US9346797, 14 | US9346797, 3 | US...)
Affinity DataKi:  8.5nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230869BDBM230869(US10045974, 13 | US9346797, 13 | US9346797, 5 | US...)
Affinity DataKi:  14nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230874BDBM230874(US10045974, 10 | US9346797, 10 | US10603310, Compo...)
Affinity DataKi:  16nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230865BDBM230865(US10045974, 1 | US9346797, 1 | US10603310, Compoun...)
Affinity DataKi:  18nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230867BDBM230867(US10045974, 14 | US9346797, 14 | US9346797, 3 | US...)
Affinity DataKi:  18nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230868BDBM230868(US10045974, 4 | US9346797, 4 | US10603310, Compoun...)
Affinity DataKi:  20nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230870BDBM230870(US10045974, 6 | US9346797, 6 | US10603310, Compoun...)
Affinity DataKi:  20nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230866BDBM230866(US10045974, 2 | US9346797, 2 | US10603310, Compoun...)
Affinity DataKi:  23nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 230872BDBM230872(US10045974, 8 | US9346797, 8 | US10603310, Compoun...)
Affinity DataKi:  71nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent