Compile Data Set for Download or QSAR
Report error Found 112 Enz. Inhib. hit(s) with all data for entry = 9072
TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439120BDBM439120(US10604502, Ex # 108)
Affinity DataIC50: 1nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439100BDBM439100(US10604502, Ex # 88)
Affinity DataIC50: 1nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439039BDBM439039(US10604502, Ex # 27)
Affinity DataIC50: 2nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439089BDBM439089(US10604502, Ex # 77)
Affinity DataIC50: 2nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439014BDBM439014(US10604502, Ex # 2)
Affinity DataIC50: 2nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439109BDBM439109(3-(2,2-dimethyl-1,2,3,4-tetrahydroquinolin-5-yl)-1...)
Affinity DataIC50: 3nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439056BDBM439056(US10604502, Ex # 44)
Affinity DataIC50: 4nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439101BDBM439101(3-(2,2-dimethyl-1,2,3,4-tetrahydro-1,7-naphthyridi...)
Affinity DataIC50: 4nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439046BDBM439046(US10604502, Ex # 34)
Affinity DataIC50: 4nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439090BDBM439090(US10604502, Ex # 78)
Affinity DataIC50: 5nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439121BDBM439121(1-((1R,4R)-1-aminosulfonylcyclohexyl)-6-methyl-3-(...)
Affinity DataIC50: 5nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439036BDBM439036(3-(3-amino-2-methylphenyl)-1-(3-hydroxypropyl)-2,6...)
Affinity DataIC50: 5nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439015BDBM439015(US10604502, Ex # 3)
Affinity DataIC50: 5nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439107BDBM439107(US10604502, Ex # 95)
Affinity DataIC50: 5nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439024BDBM439024(US10604502, Ex # 12)
Affinity DataIC50: 6nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439122BDBM439122(US10604502, Ex # 110)
Affinity DataIC50: 6nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439021BDBM439021(US10604502, Ex # 9)
Affinity DataIC50: 6nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439059BDBM439059(US10604502, Ex # 47)
Affinity DataIC50: 6nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439091BDBM439091(US10604502, Ex # 79)
Affinity DataIC50: 6nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439124BDBM439124(1-((1R,4R)-4-cyanocyclohexyl)-6-methyl-3-(5-amino-...)
Affinity DataIC50: 8nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439123BDBM439123(US10604502, Ex # 111)
Affinity DataIC50: 8nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439079BDBM439079(US10604502, Ex # 67)
Affinity DataIC50: 9nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439108BDBM439108(US10604502, Ex # 96)
Affinity DataIC50: 9nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439092BDBM439092(3-(5-amino-4-chloropyridin-3-yl)-6-methyl-1-(5-(me...)
Affinity DataIC50: 10nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439013BDBM439013(US10604502, Ex # 1)
Affinity DataIC50: 10nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439041BDBM439041(US10604502, Ex # 29)
Affinity DataIC50: 12nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439033BDBM439033(US10604502, Ex # 21)
Affinity DataIC50: 12nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439093BDBM439093(US10604502, Ex # 81)
Affinity DataIC50: 12nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439077BDBM439077(US10604502, Ex # 65)
Affinity DataIC50: 13nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439038BDBM439038(US10604502, Ex # 26)
Affinity DataIC50: 14nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439062BDBM439062(US10604502, Ex # 50)
Affinity DataIC50: 14nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439094BDBM439094(US10604502, Ex # 82)
Affinity DataIC50: 15nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439074BDBM439074(US10604502, Ex # 62)
Affinity DataIC50: 16nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439080BDBM439080(3(3-(5-amino-4-chloropyridin-3-yl)-5-cyano-6-methy...)
Affinity DataIC50: 16nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439044BDBM439044(US10604502, Ex # 32)
Affinity DataIC50: 16nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439022BDBM439022(US10604502, Ex # 10)
Affinity DataIC50: 17nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439069BDBM439069(US10604502, Ex # 57)
Affinity DataIC50: 18nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439064BDBM439064(US10604502, Ex # 52)
Affinity DataIC50: 18nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439086BDBM439086(US10604502, Ex # 74)
Affinity DataIC50: 20nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439066BDBM439066(US10604502, Ex # 54)
Affinity DataIC50: 23nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439075BDBM439075(US10604502, Ex # 63)
Affinity DataIC50: 23nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439026BDBM439026(US10604502, Ex # 14)
Affinity DataIC50: 24nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439047BDBM439047(US10604502, Ex # 35)
Affinity DataIC50: 25nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439110BDBM439110(US10604502, Ex # 98)
Affinity DataIC50: 25nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439057BDBM439057((1R,4R)-4-(3-(5-amino-4-chloropyridin-3-yl)-5-cyan...)
Affinity DataIC50: 26nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439016BDBM439016(US10604502, Ex # 15 | US10604502, Ex # 4)
Affinity DataIC50: 26nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439016BDBM439016(US10604502, Ex # 15 | US10604502, Ex # 4)
Affinity DataIC50: 27nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439023BDBM439023(US10604502, Ex # 11)
Affinity DataIC50: 28nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439019BDBM439019(US10604502, Ex # 7)
Affinity DataIC50: 28nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439095BDBM439095(US10604502, Ex # 83)
Affinity DataIC50: 28nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

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