Compile Data Set for Download or QSAR
Report error Found 135 Enz. Inhib. hit(s) with all data for entry = 9141
LigandChemical structure of BindingDB Monomer ID 444935BDBM444935(6-((4'-fluoro-3-methoxy-3'-(trifluoromethoxy)-4- |...)
Affinity DataIC50: 4nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444908BDBM444908(US10668067, Example 1-69 | 6-((2-chloro-4'-fluoro-...)
Affinity DataIC50: 6nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444931BDBM444931(6-((3'-chloro-2,4'-difluoro-5-methoxy-4- | US10668...)
Affinity DataIC50: 7nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444965BDBM444965(6-((1-(2-chloro-5-methoxy-3'-(trifluoromethyl)-[1,...)
Affinity DataIC50: 7nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444968BDBM444968(6-((carbamoyl(2-chloro-3',5-dimethoxy-5'-(trifluor...)
Affinity DataIC50: 7nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444954BDBM444954(6-((2,4'-difluoro-5-methoxy-3'-(trifluoromethoxy)-...)
Affinity DataIC50: 7nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444937BDBM444937(6-((2-chloro-4'-fluoro-5-methoxy-3'-(trifluorometh...)
Affinity DataIC50: 8nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444897BDBM444897(US10668067, Example 1-58 | 6-((2-chloro-4'-fluoro-...)
Affinity DataIC50: 9nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444847BDBM444847(6-((3',4'-dichloro-2-fluoro-5-methoxy-4- | US10668...)
Affinity DataIC50: 9nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444890BDBM444890(US10668067, Example 1-51 | 6-((2-chloro-3',5-dimet...)
Affinity DataIC50: 9nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444966BDBM444966(6-((carbamoyl(2,4'-dichloro-3'-fluoro-5-methoxy-4-...)
Affinity DataIC50: 10nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444876BDBM444876(US10668067, Example 1-37 | 6-((2-chloro-5-methoxy-...)
Affinity DataIC50: 11nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444875BDBM444875(US10668067, Example 1-36 | 6-((2-chloro-3',5-dimet...)
Affinity DataIC50: 11nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444878BDBM444878(US10668067, Example 1-39 | 6-((2-chloro-5-methoxy-...)
Affinity DataIC50: 11nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444865BDBM444865(6-((2,4'-difluoro-5-methoxy-3'-(trifluoromethyl)-4...)
Affinity DataIC50: 12nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444949BDBM444949(6-((2-chloro-4'-fluoro-5-methoxy-3'-(trifluorometh...)
Affinity DataIC50: 14nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444848BDBM444848(6-((4'-chloro-2-fluoro-5-methoxy-3'-(trifluorometh...)
Affinity DataIC50: 14nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444926BDBM444926(6-((2,4'-difluoro-5-methoxy-3'-(trifluoromethoxy)-...)
Affinity DataIC50: 14nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444871BDBM444871(6-((2,3'-dichloro-5,5'-dimethoxy-4- | US10668067, ...)
Affinity DataIC50: 14nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444938BDBM444938(6-(1-(5-Fluoro-2-methoxy-4-tetradecylphenyl)-3-met...)
Affinity DataIC50: 14nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444870BDBM444870(6-((2-chloro-5-methoxy-3'-(trifluoromethyl)-4- | U...)
Affinity DataIC50: 16nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444864BDBM444864(6-((3'-chloro-2,4'-difluoro-5,5'-dimethoxy-4- | US...)
Affinity DataIC50: 16nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444969BDBM444969(6-((carbamoyl(2-chloro-5-methoxy-3'-(2,2,2-trifluo...)
Affinity DataIC50: 16nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444851BDBM444851(6-((2-fluoro-5-methoxy-3'-(trifluoromethoxy)-4- | ...)
Affinity DataIC50: 17nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444955BDBM444955(6-((2,4'-difluoro-5-methoxy-3'-(trifluoromethoxy)-...)
Affinity DataIC50: 17nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444894BDBM444894(US10668067, Example 1-55 | 6-((2-chloro-2'-fluoro-...)
Affinity DataIC50: 17nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444936BDBM444936(6-((4'-fluoro-3-methoxy-3'-(trifluoromethyl)-4- | ...)
Affinity DataIC50: 17nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444846BDBM444846(6-((2-fluoro-3',5-dimethoxy-5'-(trifluoromethyl)-4...)
Affinity DataIC50: 18nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444930BDBM444930(6-((3′-chloro-2,4′-difluoro-5-methoxy-...)
Affinity DataIC50: 18nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444844BDBM444844(6-((2-fluoro-3',5-dimethoxy-5'-(trifluoromethoxy)-...)
Affinity DataIC50: 18nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444921BDBM444921(6-((2-fluoro-3',5-dimethoxy-5'-(trifluoromethyl)-4...)
Affinity DataIC50: 18nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444899BDBM444899(US10668067, Example 1-60 | 6-((2,3'-dichloro-4'-fl...)
Affinity DataIC50: 19nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444895BDBM444895(US10668067, Example 1-56 | 6-((2-chloro-2',5-dimet...)
Affinity DataIC50: 19nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444900BDBM444900(US10668067, Example 1-61 | 6-((2,3'-dichloro-5-met...)
Affinity DataIC50: 20nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444868BDBM444868(6-((2,4'-dichloro-5-methoxy-3'-methyl-4- | US10668...)
Affinity DataIC50: 20nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444866BDBM444866(6-((2,4'-difluoro-5-methoxy-3'-(trifluoromethoxy)-...)
Affinity DataIC50: 20nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444951BDBM444951(6-((2-chloro-4'-fluoro-5-methoxy-3'-(trifluorometh...)
Affinity DataIC50: 20nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444877BDBM444877(US10668067, Example 1-38 | 6-((2-chloro-3'-cyclopr...)
Affinity DataIC50: 21nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444907BDBM444907(US10668067, Example 1-68 | 6-((2-chloro-3',4'-difl...)
Affinity DataIC50: 23nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444896BDBM444896(US10668067, Example 1-57 | 6-((2-chloro-4'-fluoro-...)
Affinity DataIC50: 24nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444953BDBM444953(6-((2-chloro-4'-fluoro-5-methoxy-3'-(trifluorometh...)
Affinity DataIC50: 24nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444934BDBM444934(6-((5-chloro-2-methoxy-4-(2-methoxy-6-((trifluorom...)
Affinity DataIC50: 26nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444952BDBM444952(6-((2-chloro-4'-fluoro-5-methoxy-3'-(trifluorometh...)
Affinity DataIC50: 26nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444873BDBM444873(US10668067, Example 1-34 | 6-((2,5'-dichloro-5-met...)
Affinity DataIC50: 27nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444948BDBM444948(6-((2-chloro-4'-fluoro-5-methoxy-3'-(trifluorometh...)
Affinity DataIC50: 28nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444902BDBM444902(US10668067, Example 1-63 | 6-((2,4'-dichloro-3'-fl...)
Affinity DataIC50: 28nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444869BDBM444869(6-((2,3'-dichloro-5'-fluoro-5-methoxy-4- | US10668...)
Affinity DataIC50: 28nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444888BDBM444888(US10668067, Example 1-49 | 6-((2-chloro-3'-fluoro-...)
Affinity DataIC50: 28nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444881BDBM444881(US10668067, Example 1-42 | 6-((5-chloro-2-methoxy-...)
Affinity DataIC50: 29nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 444943BDBM444943(6-((2-chloro-4'-fluoro-5-methoxy-3'-(2,2,2-trifluo...)
Affinity DataIC50: 31nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

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