Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 9145
TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445062BDBM445062(US10669227, Compound 6)
Affinity DataIC50: 1.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 191770BDBM191770(US9187406, Compound 7 | US10669227, Compound 7 | U...)
Affinity DataIC50: 1.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50092158BDBM50092158(CHEMBL415879 | cid_1318 | 1,10-phenanthroline | US...)
Affinity DataIC50: 4.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetMatrix metalloproteinase-9(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445061BDBM445061(US10669227, Compound 3)
Affinity DataIC50: 6.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445061BDBM445061(US10669227, Compound 3)
Affinity DataIC50: 8.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetMatrix metalloproteinase-9(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50092158BDBM50092158(CHEMBL415879 | cid_1318 | 1,10-phenanthroline | US...)
Affinity DataIC50: 9.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetNeutrophil collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 191763BDBM191763(US9187406, Curcumin | US9187397, 1 | curcumin | US...)
Affinity DataIC50: 1.40E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445058BDBM445058(US10669227, Compound 1 | US11608309, Compound 1)
Affinity DataIC50: 1.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetMatrix metalloproteinase-9(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445058BDBM445058(US10669227, Compound 1 | US11608309, Compound 1)
Affinity DataIC50: 1.60E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetMatrix metalloproteinase-9(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445060BDBM445060(US10669227, Compound 4)
Affinity DataIC50: 1.70E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetNeutrophil collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50092158BDBM50092158(CHEMBL415879 | cid_1318 | 1,10-phenanthroline | US...)
Affinity DataIC50: 2.25E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetNeutrophil collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445059BDBM445059(US10669227, Compound 5 | US11608309, Compound 5)
Affinity DataIC50: 2.80E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetMatrix metalloproteinase-9(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 191763BDBM191763(US9187406, Curcumin | US9187397, 1 | curcumin | US...)
Affinity DataIC50: 2.90E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetNeutrophil collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445058BDBM445058(US10669227, Compound 1 | US11608309, Compound 1)
Affinity DataIC50: 3.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445064BDBM445064(US10669227, Compound 8)
Affinity DataIC50: 4.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

Target72 kDa type IV collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445058BDBM445058(US10669227, Compound 1 | US11608309, Compound 1)
Affinity DataIC50: 4.80E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

Target72 kDa type IV collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445061BDBM445061(US10669227, Compound 3)
Affinity DataIC50: 7.00E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

Target72 kDa type IV collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50092158BDBM50092158(CHEMBL415879 | cid_1318 | 1,10-phenanthroline | US...)
Affinity DataIC50: 7.00E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

Target72 kDa type IV collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 191763BDBM191763(US9187406, Curcumin | US9187397, 1 | curcumin | US...)
Affinity DataIC50: 8.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

Target72 kDa type IV collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445062BDBM445062(US10669227, Compound 6)
Affinity DataIC50: 8.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 191763BDBM191763(US9187406, Curcumin | US9187397, 1 | curcumin | US...)
Affinity DataIC50: 1.10E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

Target72 kDa type IV collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 191770BDBM191770(US9187406, Compound 7 | US10669227, Compound 7 | U...)
Affinity DataIC50: 1.25E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445060BDBM445060(US10669227, Compound 4)
Affinity DataIC50: 2.50E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

Target72 kDa type IV collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445060BDBM445060(US10669227, Compound 4)
Affinity DataIC50: 2.50E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent