Compile Data Set for Download or QSAR
Report error Found 117 Enz. Inhib. hit(s) with all data for entry = 9149
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445349((S)-3-(2-(((S)-1-(1-(4-cyclopropylphenyl)-1H-imida...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445348(Using the same manner as in Example 1, Compound 61...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445350((S)-1-(2-(((S)-1-(1-(3-fluoro-4-chlorophenyl)-1H-i...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445345(US10682352, Compound 58 | US10682352, Compound 96 ...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445344(US10682352, Compound 57 | (S)-3-(2-(((S)-1-(1-(3-c...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445327(US10682352, Compound 47 | US10682352, Compound 53 ...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445342(US10682352, Compound 55 | (S)-4-isopropyl-1-methyl...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445334(US10682352, Compound 50 | (S)-3-(2-((1-(1-(5-chlor...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445332(US10682352, Compound 49 | (S)-1-(2-(((S)-1-(1-(3-c...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445337(US10682352, Compound 52 | (S)-3-(2-((S)-1-(1-(3-cy...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445288(US10682352, Compound 17 | US10682352, Compound 85 ...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445364((S)-3-(6-chloro-2-(((S)-1-(1-(4-fluorophenyl)-1H-i...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445367((S)-3-(2-(((S)-1-(1-(4-chlorophenyl)-1H-imidazol-4...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445363(Using the same manner as in Example 1, Compound 76...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445352((S)-3-(2-(((S)-1-(1-(4-chloro-3-methoxyphenyl)-1H-...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445355(Using the same manner as in Example 1, Compound 68...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445381(US10682352, Compound 94)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445380((5S)-1-(2-(((S)-1-(1-(4-trifluoromethylphenyl)-1H-...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445345(US10682352, Compound 58 | US10682352, Compound 96 ...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445382((4S)-4-isopropyl-1,5-methyl-3-(2-(((S)-1-(1-(4-tri...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445377(US10682352, Compound 90)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445288(US10682352, Compound 17 | US10682352, Compound 85 ...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445379(US10682352, Compound 92)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445378((5S)-1-(2-(((S)-1-(1-(4-chlorophenyl)-1H-imidazol-...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445373(US10682352, Compound 86)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445288(US10682352, Compound 17 | US10682352, Compound 85 ...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445370(US10682352, Compound 88 | (S)-1-(2-(((S)-1-(1-(4-(...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445374((5S)-1-(2-(((S)-1-(1-(4-chlorophenyl)-1H-imidazol-...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445269(US10682352, Compound 4 | (S)-1-(2-(((S)-1-(1-(4-ch...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445345(US10682352, Compound 58 | US10682352, Compound 96 ...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445370(US10682352, Compound 88 | (S)-1-(2-(((S)-1-(1-(4-(...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445299(US10682352, Compound 26 | US10682352, Compound 110...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445345(US10682352, Compound 58 | US10682352, Compound 96 ...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445305(US10682352, Compound 31 | US10682352, Compound 111...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445393((S)-8-isopropyl-5-methyl-7-(2-(((S)-1-(1-(4-triflu...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445392((S)-8-isopropyl-7-(2-(((S)-1-(1-(4-trifluoromethyl...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445393((S)-8-isopropyl-5-methyl-7-(2-(((S)-1-(1-(4-triflu...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445389((S)-7-isopropyl-6-(2-(((S)-1-(1-(4-(trifluoromethy...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445388((S)-5-isopropyl-4,4-dimethyl-1-(2-(((S)-1-(1-(4-(t...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445391(US10682352, Compound 104)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445385(US10682352, Compound 98)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445384((S)-3-(2-((1-(1-(3-chloro-5-fluorophenyl)-1H-imida...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445387((S)-6-(2-(((S)-1-(1-(4-chlorophenyl)-1H-imidazol-4...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM363689(US9850277, Compound 176 | US10682352, Compound AG1...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445403((S)-4-isopropyl-1-trideuteromethyl-3-(2-(((S)-1-(5...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445401(US10682352, Compound 115 | (S)-1-(2-(((S)-1-(2R...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445275(US10682352, Compound 10 | (S)-1-(2-(((S)-1-(1-(4-c...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445270(US10682352, Compound 5 | US10682352, Compound 51 |...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445269(US10682352, Compound 4 | (S)-1-(2-(((S)-1-(1-(4-ch...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445268(US10682352, Compound 3 | (R)-1-(2-(((S)-1-(1-(4-ch...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

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