Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 9207
TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449138(US10702498, Compound 12 | US11484525, Compound 12)
Affinity DataKi:  42nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449170(US10702498, Compound 14 | US11484525, Compound 14)
Affinity DataKi:  87nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449177(US10702498, Compound 15 | US11484525, Compound 15)
Affinity DataKi:  130nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetTumor protein p53-inducible nuclear protein 2(Human)
University of California

US Patent
LigandPNGBDBM449138(US10702498, Compound 12 | US11484525, Compound 12)
Affinity DataEC50:  180nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetTumor protein p53-inducible nuclear protein 2(Human)
University of California

US Patent
LigandPNGBDBM449170(US10702498, Compound 14 | US11484525, Compound 14)
Affinity DataEC50:  440nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449046(US10702498, Compound 8 | US11484525, Compound 8)
Affinity DataKi:  460nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449138(US10702498, Compound 12 | US11484525, Compound 12)
Affinity DataKi:  460nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449170(US10702498, Compound 14 | US11484525, Compound 14)
Affinity DataKi:  510nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449139(US10702498, Compound 13 | US11484525, Compound 13)
Affinity DataKi:  550nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449046(US10702498, Compound 8 | US11484525, Compound 8)
Affinity DataKi:  820nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449139(US10702498, Compound 13 | US11484525, Compound 13)
Affinity DataKi:  1.02E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449052(US10702498, Compound 9 | US11484525, Compound 9)
Affinity DataKi:  1.36E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449090(US10702498, Compound 11 | US11484525, Compound 11)
Affinity DataKi:  1.86E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449031(US10702498, Compound 4 | US11484525, Compound 4)
Affinity DataKi:  2.30E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449045(US10702498, Compound 7 | US11484525, Compound 7)
Affinity DataKi:  2.50E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetTumor protein p53-inducible nuclear protein 2(Human)
University of California

US Patent
LigandPNGBDBM449139(US10702498, Compound 13 | US11484525, Compound 13)
Affinity DataEC50:  3.10E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449033(US10702498, Compound 5 | US11484525, Compound 5)
Affinity DataKi:  4.70E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449069(US10702498, Compound 10 | US11484525, Compound 10)
Affinity DataKi:  4.75E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449028(US10702498, Compound 2 | US11484525, Compound 2)
Affinity DataKi:  5.80E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetTumor protein p53-inducible nuclear protein 2(Human)
University of California

US Patent
LigandPNGBDBM449046(US10702498, Compound 8 | US11484525, Compound 8)
Affinity DataEC50:  6.60E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449027(US10702498, Compound 1)
Affinity DataKi:  7.20E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449036(US10702498, Compound 6)
Affinity DataKi:  1.00E+4nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449030(US10702498, Compound 3 | US11484525, Compound 3)
Affinity DataKi:  1.38E+4nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449069(US10702498, Compound 10 | US11484525, Compound 10)
Affinity DataKi: <5.00E+4nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449052(US10702498, Compound 9 | US11484525, Compound 9)
Affinity DataKi: <5.00E+4nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449177(US10702498, Compound 15 | US11484525, Compound 15)
Affinity DataKi: <5.00E+4nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449090(US10702498, Compound 11 | US11484525, Compound 11)
Affinity DataKi: <5.00E+4nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent