Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 9240
TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451264(US10709718, Compound 3)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451262(US10709718, Compound 1)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451398(US10709718, Compound 23)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451396(US10709718, Compound 21)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451394(US10709718, Compound 19)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451395(US10709718, Compound 20)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451392(US10709718, Compound 17)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451390(US10709718, Compound 13)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451391(US10709718, Compound 14)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451388(US10709718, Compound 11)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451382(US10709718, Compound 9)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451387(US10709718, Compound 10)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451381(US10709718, Compound 8)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451327(US10709718, Compound 5)
Affinity DataIC50: 10nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451263(US10709718, Compound 2)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451397(US10709718, Compound 22)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451393(US10709718, Compound 18)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451406(US10709718, Compound 34)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451404(US10709718, Compound 32)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451405(US10709718, Compound 33)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451389(US10709718, Compound 12)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451402(US10709718, Compound 30)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451403(US10709718, Compound 31)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451400(US10709718, Compound 25)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451401(US10709718, Compound 26)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451370(US10709718, Compound 7)
Affinity DataIC50: 550nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451399(US10709718, Compound 24)
Affinity DataIC50: 550nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451368(US10709718, Compound 6)
Affinity DataIC50: 550nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent