Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 9466
TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468574BDBM468574(US10806794, Compound mPEG7-NHCO-Saquinavir)
Affinity DataIC50: 0.0500nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468573BDBM468573(US10806794, Compound mPEG5-NHCO-Saquinavir)
Affinity DataIC50: 0.0500nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50213021BDBM50213021(CHEBI:63621 | Fortovase | Invirase | Ro-31-8959 | ...)
Affinity DataIC50: 0.0500nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468572BDBM468572(US10806794, Compound mPEG3-NHCO-Saquinavir)
Affinity DataIC50: 0.0700nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468568BDBM468568(US10806794, Compound mPEG1-OCONH-Tipranavir)
Affinity DataIC50: 0.188nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468563BDBM468563(US10806794, Compound mPEG5-O-Darunavir)
Affinity DataIC50: 0.210nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468567BDBM468567(US10806794, Compound mPEG0-OCONH-Tipranavir)
Affinity DataIC50: 0.292nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468564BDBM468564(US10806794, Compound mPEG7-O-Darunavir)
Affinity DataIC50: 0.358nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468366BDBM468366(US10806794, Compound mono-mPEG3-Atazanavir)
Affinity DataIC50: 0.366nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468570BDBM468570(US10806794, Compound mPEG5-OCONH-Tipranavir)
Affinity DataIC50: 0.462nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468562BDBM468562(US10806794, Compound mPEG3-O-Darunavir)
Affinity DataIC50: 0.475nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468569BDBM468569(US10806794, Compound mPEG3-OCONH-Tipranavir)
Affinity DataIC50: 0.617nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468560BDBM468560(US10806794, Compound mPEG5-N-Darunavir)
Affinity DataIC50: 1.10nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468557BDBM468557(US10806794, Compound mono-mPEG7-Atazanavir)
Affinity DataIC50: 1.29nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468372BDBM468372(US10806794, Compound mono-mPEG6-Atazanavir)
Affinity DataIC50: 1.31nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 8125BDBM8125(Darunavir (DRV) | CHEMBL1323 | (3R,3aS,6aR)-hexahy...)
Affinity DataIC50: 1.5nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468365BDBM468365(US10806794, Compound mono-mPEG1-Atazanavir)
Affinity DataIC50: 2.82nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468370BDBM468370(US10806794, Compound mono-mPEG5-Atazanavir)
Affinity DataIC50: 2.91nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468561BDBM468561(US10806794, Compound mPEG7-N-Darunavir)
Affinity DataIC50: 5.20nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468559BDBM468559(US10806794, Compound mPEG3-N-Darunavir)
Affinity DataIC50: 5.30nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 13934BDBM13934(CGP 73547 | CHEMBL1163 | methyl N-[(1S)-1-{[(2S,3S...)
Affinity DataIC50: 6.92nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50479982BDBM50479982(CHEBI:63628 | Aptivus | Tipranavir | U-140690 | US...)
Affinity DataIC50: 7.20nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50067593BDBM50067593(CHEBI:44032 | Crixivan | Indinavir | L-735524 | MK...)
Affinity DataIC50: 10.5nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468305BDBM468305(US10806794, Compound di-mPEG7-Atazanavir)
Affinity DataIC50: 10.9nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468566BDBM468566(US10806794, Compound mPEG7-amide-Tipranavir)
Affinity DataIC50: 12.2nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468300BDBM468300(US10806794, Compound di-mPEG3-Atazanavir)
Affinity DataIC50: 12.7nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468303BDBM468303(US10806794, Compound di-mPEG6-Atazanavir)
Affinity DataIC50: 15.6nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 468301BDBM468301(US10806794, Compound di-mPEG5-Atazanavir)
Affinity DataIC50: 17.3nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent