Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 9527
TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472836(3-[3-Dimethylaminomethyl-4-hydroxy-1-(3-phenyl-pro...)
Affinity DataEC50:  10nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataEC50: <10nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472721(3-(3-((Dimethylamino)methyl)-4-hydroxy-1-phenethyl...)
Affinity DataEC50:  34nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM224017((+)-Morphine | US10752592, Compound morphine | US1...)
Affinity DataEC50:  60nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataEC50:  60nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472832(US10836728, Compound (15))
Affinity DataEC50:  67nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472704(3-(1-(2-Chloro-4-fluorobenzyl)-3-((dimethylamino)m...)
Affinity DataEC50:  102nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472835(3-(3-((Dimethylamino)methyl)-4-hydroxy-1-(4-hydrox...)
Affinity DataEC50:  160nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472714(US10836728, Compound Ent-A-syn-(6))
Affinity DataEC50:  163nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472836(3-[3-Dimethylaminomethyl-4-hydroxy-1-(3-phenyl-pro...)
Affinity DataEC50:  270nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM224017((+)-Morphine | US10752592, Compound morphine | US1...)
Affinity DataEC50:  310nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472715(US10836728, Compound Ent-B-syn-(6))
Affinity DataEC50:  463nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472834(US10836728, Compound (17))
Affinity DataEC50:  467nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472831(US10836728, Compound (11))
Affinity DataEC50:  550nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472721(3-(3-((Dimethylamino)methyl)-4-hydroxy-1-phenethyl...)
Affinity DataEC50:  830nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472704(3-(1-(2-Chloro-4-fluorobenzyl)-3-((dimethylamino)m...)
Affinity DataEC50:  2.56E+3nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472835(3-(3-((Dimethylamino)methyl)-4-hydroxy-1-(4-hydrox...)
Affinity DataEC50:  3.10E+3nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472714(US10836728, Compound Ent-A-syn-(6))
Affinity DataEC50:  3.17E+3nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472715(US10836728, Compound Ent-B-syn-(6))
Affinity DataEC50:  3.67E+3nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472831(US10836728, Compound (11))
Affinity DataEC50:  1.07E+4nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472834(US10836728, Compound (17))
Affinity DataEC50: >1.00E+5nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472832(US10836728, Compound (15))
Affinity DataEC50: >1.00E+5nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
US Patent