Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 9586
TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395712(US10308648, Compound 107 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395711(US10308648, Compound 106 | (1S,3R) N-(4-aminophen...)
Affinity DataIC50: 100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395710(US10308648, Compound 105 | N-((1S,3R)-3-((5-chloro...)
Affinity DataIC50: 100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM475935(US10865206, Compound 101)
Affinity DataIC50: 100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395714(US10308648, Compound 109 | US10865206, Compound 10...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395709(US10308648, Compound 104 | 4-amino-N-(5-(5-chloro-...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395708(US10308648, Compound 103 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395707(US10308648, Compound 102 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395718(US10308648, Compound 113 | N1-(4-(((1S,3R)-3-((5-c...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395717(US10308648, Compound 112 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395716(US10308648, Compound 111 | 4-amino-N-(1S,3R)-3-(5-...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM475948(US10865206, Compound 110)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395713(US10308648, Compound 108 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM475931(US10865206, Compound 100)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM475952(US10865206, Compound 114)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available Adapta kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent