Compile Data Set for Download or QSAR
Report error Found 88 Enz. Inhib. hit(s) with all data for entry = 9679
TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481164BDBM481164(US10906905, Example 4-1)
Affinity DataIC50: 2nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481161BDBM481161(6-((5S,8R)-2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrah...)
Affinity DataIC50: 3nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481203BDBM481203(6-((5R,8S)-2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrah...)
Affinity DataIC50: 3nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481162BDBM481162((5S,8R)-2-(6-Methylpyridin-2-yl)-3-(2-(4-(methylsu...)
Affinity DataIC50: 4nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481205BDBM481205(US10906905, Example 12-1)
Affinity DataIC50: 6nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481206BDBM481206(US10906905, Example 12-2)
Affinity DataIC50: 7nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481168BDBM481168(US10906905, Example 6-1)
Affinity DataIC50: 7nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481169BDBM481169(US10906905, Example 6-2)
Affinity DataIC50: 8nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481147BDBM481147(6-((5S,8R)-2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrah...)
Affinity DataIC50: 9nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481191BDBM481191(4-(2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrahydro-5,8...)
Affinity DataIC50: 9nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481174BDBM481174(3-(2-(1-Methyl-1H-pyrazol-4-yl)pyridin-4-yl)-2-(6-...)
Affinity DataIC50: 9nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481199BDBM481199(3-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-2-(6-methyl...)
Affinity DataIC50: 9nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481201BDBM481201((5S,8R)-2-(5-Fluoropyridin-2-yl)-3-(2-(1-methyl-1H...)
Affinity DataIC50: 10nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481175BDBM481175(4-(4-((5S,8R)-2-(6-Methylpyridin-2-yl)-5,6,7,8-tet...)
Affinity DataIC50: 11nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481194BDBM481194(4-(2-(6-Methylpyridin-2-yl)-4,5,6,7-tetrahydro-4,7...)
Affinity DataIC50: 12nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481193BDBM481193(4-(2-(6-Methylpyridin-2-yl)-4,5,6,7-tetrahydro-4,7...)
Affinity DataIC50: 12nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481186BDBM481186(US10906905, Example 9-2)
Affinity DataIC50: 13nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481185BDBM481185(US10906905, Example 9-1)
Affinity DataIC50: 13nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481189BDBM481189(6-(2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrahydro-5,8...)
Affinity DataIC50: 14nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481148BDBM481148(6-((5R,8S)-2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrah...)
Affinity DataIC50: 16nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481173BDBM481173(3-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-2-(6-methyl...)
Affinity DataIC50: 16nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481165BDBM481165(US10906905, Example 4-2)
Affinity DataIC50: 18nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481170BDBM481170(2-((7-(2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrahydro...)
Affinity DataIC50: 20nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481204BDBM481204(2-(6-Methylpyridin-2-yl)-3-(2-(1-(methylsulfonyl)-...)
Affinity DataIC50: 21nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481197BDBM481197(6-(2-(6-Methylpyridin-2-yl)-4,5,6,7-tetrahydro-4,7...)
Affinity DataIC50: 21nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481188BDBM481188((5R,8S)-2-(6-Methylpyridin-2-yl)-3-(2-(4-(methylsu...)
Affinity DataIC50: 23nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481172BDBM481172(2-(2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrahydro-5,8...)
Affinity DataIC50: 25nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481196BDBM481196(US10906905, Example 35-2)
Affinity DataIC50: 25nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481200BDBM481200(6-((5S,8R)-2-(5-Fluoropyridin-2-yl)-5,6,7,8-tetrah...)
Affinity DataIC50: 26nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481167BDBM481167(2-(6-Methylpyridin-2-yl)-3-(quinoxalin-6-yl)-5,6,7...)
Affinity DataIC50: 26nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481202BDBM481202(4-(4-((5S,8R)-2-(5-Fluoropyridin-2-yl)-5,6,7,8-tet...)
Affinity DataIC50: 28nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481181BDBM481181(US10906905, Example 17-2)
Affinity DataIC50: 28nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481180BDBM481180(US10906905, Example 17-1)
Affinity DataIC50: 28nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481163BDBM481163(4-(4-(2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrahydro-...)
Affinity DataIC50: 29nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481207BDBM481207(6-((5S,8R)-2-(Pyridin-2-yl)-5,6,7,8-tetrahydro-5,8...)
Affinity DataIC50: 29nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481176BDBM481176(4-((4-(2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrahydro...)
Affinity DataIC50: 31nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481192BDBM481192(2-(6-Methylpyridin-2-yl)-3-(2-(4-(methylsulfonyl)p...)
Affinity DataIC50: 34nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481208BDBM481208((5S,8R)-3-(2-(4-(Methylsulfonyl)phenyl)pyridin-4-y...)
Affinity DataIC50: 34nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481179BDBM481179(4-(4-(2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrahydro-...)
Affinity DataIC50: 38nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481195BDBM481195(US10906905, Example 35-1)
Affinity DataIC50: 39nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481209BDBM481209(7-((5S,8R)-2-(Pyridin-2-yl)-5,6,7,8-tetrahydro-5,8...)
Affinity DataIC50: 39nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481171BDBM481171(6-(2-(5-Fluoropyridin-2-yl)-5,6,7,8-tetrahydro-5,8...)
Affinity DataIC50: 43nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481166BDBM481166(2-((4-((5S,8R)-2-(6-Methylpyridin-2-yl)-5,6,7,8-te...)
Affinity DataIC50: 46nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481198BDBM481198(2-((4-(2-(6-Methylpyridin-2-yl)-4,5,6,7-tetrahydro...)
Affinity DataIC50: 52nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481190BDBM481190(Tert-butyl (4-(2-(6-methylpyridin-2-yl)-5,6,7,8-te...)
Affinity DataIC50: 55nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481183BDBM481183(2-((4-(2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrahydro...)
Affinity DataIC50: 59nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481177BDBM481177(2-(6-Methylpyridin-2-yl)-3-(4-(piperidin-4-yloxy)q...)
Affinity DataIC50: 60nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481178BDBM481178(4-((5S,8R)-2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrah...)
Affinity DataIC50: 77nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481182BDBM481182((S)-1-((4-((5S,8R)-2-(6-Methylpyridin-2-yl)-5,6,7,...)
Affinity DataIC50: 80nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 481187BDBM481187(4-(2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrahydro-5,8...)
Affinity DataIC50: 85nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

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