TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 4.60nMAssay Description:In the case of Km ATP, EGFR T790M/L858R protein kinase activity was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009)...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: <100nMAssay Description:Activity of BTK protein kinase was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009). The compound of the present dis...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: <100nMAssay Description:Activity of BTK protein kinase was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009). The compound of the present dis...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: <100nMAssay Description:Activity of BTK protein kinase was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009). The compound of the present dis...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: <100nMAssay Description:Activity of BTK protein kinase was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009). The compound of the present dis...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 195nMAssay Description:The inhibitory activities of the compound to Tec, Txk, and ITK of human were performed by Eurofins Pharma Discovery Services UK Limited (UK) of the U...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 218nMAssay Description:The inhibitory activities of the compound to Tec, Txk, and ITK of human were performed by Eurofins Pharma Discovery Services UK Limited (UK) of the U...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 550nMAssay Description:Activity of BTK protein kinase was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009). The compound of the present dis...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 4.54E+3nMAssay Description:The inhibitory activities of the compound to Tec, Txk, and ITK of human were performed by Eurofins Pharma Discovery Services UK Limited (UK) of the U...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 5.00E+3nMAssay Description:The inhibitory activities of the compound to Tec, Txk, and ITK of human were performed by Eurofins Pharma Discovery Services UK Limited (UK) of the U...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: >5.00E+3nMAssay Description:The inhibitory activities of the compound to Tec, Txk, and ITK of human were performed by Eurofins Pharma Discovery Services UK Limited (UK) of the U...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 5.50E+3nMAssay Description:Activity of BTK protein kinase was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009). The compound of the present dis...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 5.50E+3nMAssay Description:Activity of BTK protein kinase was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009). The compound of the present dis...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Activity of BTK protein kinase was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009). The compound of the present dis...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Activity of BTK protein kinase was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009). The compound of the present dis...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:In the case of Km ATP, EGFR T790M/L858R protein kinase activity was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009)...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Activity of BTK protein kinase was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009). The compound of the present dis...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitory activities of the compound to Tec, Txk, and ITK of human were performed by Eurofins Pharma Discovery Services UK Limited (UK) of the U...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:In the case of Km ATP, EGFR T790M/L858R protein kinase activity was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009)...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Activity of BTK protein kinase was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009). The compound of the present dis...More data for this Ligand-Target Pair