Compile Data Set for Download or QSAR
Report error Found 67 Enz. Inhib. hit(s) with all data for entry = 9712
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374770BDBM374770(US10246467, Example I-68 | US10246467, Example I-6...)
Affinity DataIC50: 3nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374793BDBM374793(US10246467, Example I-115 | US10246467, Example I-...)
Affinity DataIC50: 4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374773BDBM374773(US10246467, Example I-70 | US10919913, # I-70 | US...)
Affinity DataIC50: 4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374730BDBM374730(US10246467, Example I-2 | US10246467, Example I-1 ...)
Affinity DataIC50: 5nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374736BDBM374736(US10246467, Example I-8 | US10246467, Example I-7 ...)
Affinity DataIC50: 5nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374796BDBM374796(US10246467, Example I-117 | US10919913, # I-117 | ...)
Affinity DataIC50: 6nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374777BDBM374777(US10246467, Example I-78 | US10919913, # I-80 | US...)
Affinity DataIC50: 6nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374777BDBM374777(US10246467, Example I-78 | US10919913, # I-80 | US...)
Affinity DataIC50: 7nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374789BDBM374789(US10246467, Example I-110 | US10246467, Example I-...)
Affinity DataIC50: 7nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374770BDBM374770(US10246467, Example I-68 | US10246467, Example I-6...)
Affinity DataIC50: 7nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374733BDBM374733(US10246467, Example I-5 | US10246467, Example I-4 ...)
Affinity DataIC50: 7nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374733BDBM374733(US10246467, Example I-5 | US10246467, Example I-4 ...)
Affinity DataIC50: 8nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374779BDBM374779(US10246467, Example I-82 | US10919913, # I-82 | US...)
Affinity DataIC50: 8nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374730BDBM374730(US10246467, Example I-2 | US10246467, Example I-1 ...)
Affinity DataIC50: 9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374793BDBM374793(US10246467, Example I-115 | US10246467, Example I-...)
Affinity DataIC50: 9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374736BDBM374736(US10246467, Example I-8 | US10246467, Example I-7 ...)
Affinity DataIC50: 9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374750BDBM374750(US10246467, Example I-33 | US10246467, Example I-3...)
Affinity DataIC50: 9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374748BDBM374748(US10246467, Example I-30 | US10919913, # I-30 | US...)
Affinity DataIC50: 10nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374739BDBM374739(US10246467, Example I-11 | US10246467, Example I-1...)
Affinity DataIC50: 10nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374783BDBM374783(US10246467, Example I-88 | US10919913, # I-88 | US...)
Affinity DataIC50: 10nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374789BDBM374789(US10246467, Example I-110 | US10246467, Example I-...)
Affinity DataIC50: 11nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374774BDBM374774(US10246467, Example I-72 | US10919913, # I-72 | US...)
Affinity DataIC50: 12nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374753BDBM374753(US10246467, Example I-37 | US10246467, Example I-3...)
Affinity DataIC50: 12nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374776BDBM374776(US10246467, Example I-76 | US10919913, # I-76 | US...)
Affinity DataIC50: 13nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374775BDBM374775(US10246467, Example I-74 | US10919913, # I-74 | US...)
Affinity DataIC50: 13nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374787BDBM374787(US10246467, Example I-105 | US10919913, # I-105 | ...)
Affinity DataIC50: 13nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374786BDBM374786(US10246467, Example I-92 | US10919913, # I-92 | US...)
Affinity DataIC50: 13nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374792BDBM374792(US10246467, Example I-112 | US10919913, # I-112 | ...)
Affinity DataIC50: 15nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374768BDBM374768(US10246467, Example I-63 | US10919913, # I-63 | US...)
Affinity DataIC50: 15nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374753BDBM374753(US10246467, Example I-37 | US10246467, Example I-3...)
Affinity DataIC50: 16nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374788BDBM374788(US10246467, Example I-107 | US10919913, # I-107 | ...)
Affinity DataIC50: 18nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374739BDBM374739(US10246467, Example I-11 | US10246467, Example I-1...)
Affinity DataIC50: 18nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374760BDBM374760(US10246467, Example I-47 | US10919913, # I-47 | US...)
Affinity DataIC50: 19nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374750BDBM374750(US10246467, Example I-33 | US10246467, Example I-3...)
Affinity DataIC50: 19nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374758BDBM374758(US10246467, Example I-43 | US10919913, # I-43 | US...)
Affinity DataIC50: 20nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374784BDBM374784(US10246467, Example I-90 | US10919913, # I-90 | US...)
Affinity DataIC50: 26nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374769BDBM374769(US10246467, Example I-65 | US10919913, # I-65 | US...)
Affinity DataIC50: 31nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374764BDBM374764(US10246467, Example I-55 | US10919913, # I-55 | US...)
Affinity DataIC50: 32nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374767BDBM374767(US10246467, Example I-61 | US10919913, # I-61 | US...)
Affinity DataIC50: 32nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374780BDBM374780(US10246467, Example I-84 | US10919913, # I-84 | US...)
Affinity DataIC50: 33nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374781BDBM374781(US10246467, Example I-86 | US10919913, # I-86 | US...)
Affinity DataIC50: 35nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374766BDBM374766(US10246467, Example I-59 | US10919913, # I-59 | US...)
Affinity DataIC50: 36nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374761BDBM374761(US10246467, Example I-49 | US10919913, # I-49 | US...)
Affinity DataIC50: 37nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374782BDBM374782(US10246467, Example I-87 | US10919913, # I-87 | US...)
Affinity DataIC50: 37nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374757BDBM374757(US10246467, Example I-41 | US10919913, # I-41 | US...)
Affinity DataIC50: 40nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374762BDBM374762(US10246467, Example I-51 | US10919913, # I-51 | US...)
Affinity DataIC50: 41nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374756BDBM374756(US10246467, Example I-39 | US10919913, # I-39 | US...)
Affinity DataIC50: 48nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374763BDBM374763(US10246467, Example I-53 | US10919913, # I-53 | US...)
Affinity DataIC50: 49nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374746BDBM374746(US10246467, Example I-28 | US10919913, # I-28 | US...)
Affinity DataIC50: 51nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 374742BDBM374742(US10246467, Example I-14 | US10246467, Example I-1...)
Affinity DataIC50: 51nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

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