Compile Data Set for Download or QSAR
Report error Found 1210 Enz. Inhib. hit(s) with all data for entry = 9956
TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503145BDBM503145(US11033539, Cpd. No. 10-81 | (3R)-N-[2-(1-benzylpi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502884BDBM502884(US11033539, Cpd. No. 6-35 | (2R)-2-methyl-N-(2-{1-...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502885BDBM502885(US11033539, Cpd. No. 6-36 | (2R)-N-(2-{1-[(3-fluor...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502886BDBM502886(US11033539, Cpd. No. 6-37 | (2R)-N-(2-{1-[(4-fluor...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502889BDBM502889(US11033539, Cpd. No. 6-40 | (2R)-N-(2-{1-[(3-cyano...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502891BDBM502891(US11033539, Cpd. No. 6-42 | (2R,6S)-4-(5-cyanopyri...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503264BDBM503264(US11033539, Cpd. No. 22-23 | (2R,6S)-N-[2-(1-benzy...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502871BDBM502871(US11033539, Cpd. No. 6-26 | (2R)-2-methyl-N-{2-[1-...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503143BDBM503143(US11033539, Cpd. No. 10-79 | (3R)-N-[2-(1-benzylpi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503052BDBM503052(US11033539, Cpd. No. 9-63 | N-[2-(1-benzylpiperidi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502872BDBM502872(US11033539, Cpd. No. 6-27 | (2R)-N-(2-{1-[(4-hydro...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503144BDBM503144(US11033539, Cpd. No. 10-80 | (3R)-N-[2-(1-benzylpi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502923BDBM502923(US11033539, Cpd. No. 7-1 | (2R)-N-[2-(1-benzyl-4-h...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503188BDBM503188(US11033539, Cpd. No. 17-1 | N-[2-(1-benzylpiperidi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503190BDBM503190(US11033539, Cpd. No. 17-3 | N-[2-(1-benzyl-4-hydro...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503192BDBM503192(US11033539, Cpd. No. 17-5 | N-[(2S)-2-(1-benzylpip...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502896BDBM502896(US11033539, Cpd. No. 6-46 | (2R,6S)-4-(5-cyanopyri...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502897BDBM502897(US11033539, Cpd. No. 6-47 | (2R,6S)-4-(5-cyanopyri...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502898BDBM502898(US11033539, Cpd. No. 6-48 | (2R,6S)-4-(5-cyanopyri...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502900BDBM502900(US11033539, Cpd. No. 6-50 | (2R,6S)-N-{2-[1-(1H-in...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503211BDBM503211(US11033539, Cpd. No. 18-16 | N-[2-(1-benzylpiperid...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503212BDBM503212(US11033539, Cpd. No. 18-17 | N-[2-(1-benzylpiperid...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502933BDBM502933(US11033539, Cpd. No. 7-9 | (2R)-N-[2-(1-benzylpipe...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503193BDBM503193(US11033539, Cpd. No. 17-6 | N-[(2R)-2-(1-benzylpip...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502934BDBM502934(US11033539, Cpd. No. 7-10 | (2R)-N-[(2R)-2-(1-benz...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502937BDBM502937(US11033539, Cpd. No. 7-11 | (2R)-N-[2-(1-benzyl-4-...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502938BDBM502938(US11033539, Cpd. No. 7-12 | (2R)-N-[(2R)-2-(1-benz...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503196BDBM503196(US11033539, Cpd. No. 18-1 | N-[2-(1-benzylpiperidi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502941BDBM502941(US11033539, Cpd. No. 8-1 | N-[2-(1-benzylpiperidin...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503199BDBM503199(US11033539, Cpd. No. 18-4 | N-[2-(1-benzylpiperidi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503200BDBM503200(US11033539, Cpd. No. 18-5 | N-[2-(1-benzylpiperidi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502819BDBM502819((2S,6R)-N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-(5-c...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503242BDBM503242(US11033539, Cpd. No. 21-17 | (2R)-4-[4-amino-5-(tr...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503242BDBM503242(US11033539, Cpd. No. 21-17 | (2R)-4-[4-amino-5-(tr...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502989BDBM502989(US11033539, Cpd. No. 8-48 | N-[2-(1-benzylpiperidi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503245BDBM503245(US11033539, Cpd. No. 22-2 | (2R,6S)-N-[2-(1-benzyl...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502990BDBM502990(US11033539, Cpd. No. 9-1 | N-[2-(1-benzylpiperidin...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503246BDBM503246(US11033539, Cpd. No. 22-3 | (2R,6S)-N-[2-(1-benzyl...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503247BDBM503247(US11033539, Cpd. No. 22-4 | (2R,6S)-N-[2-(1-benzyl...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502689BDBM502689(US11033539, Cpd. No. 3-1 | (2R)-N-[2-(1-benzylpipe...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503248BDBM503248(US11033539, Cpd. No. 22-5 | (2R,6S)-N-[2-(1-benzyl...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502994BDBM502994(US11033539, Cpd. No. 9-5 | (2R)-N-[(2S)-2-(1-benzy...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503250BDBM503250(US11033539, Cpd. No. 22-7 | (2R,6S)-N-[2-(1-benzyl...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502995BDBM502995(US11033539, Cpd. No. 9-6 | N-[2-(1-benzylpiperidin...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503251BDBM503251(US11033539, Cpd. No. 22-8 | (2R,6S)-N-[2-(1-benzyl...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502693BDBM502693(US11033539, Cpd. No. 3-5 | (2R)-N-[2-(1-benzyl-4-h...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502996BDBM502996(US11033539, Cpd. No. 9-7 | US11033539, Cpd. No. 9-...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503252BDBM503252(US11033539, Cpd. No. 22-9 | (2R,6S)-N-[2-(1-benzyl...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 502997BDBM502997(US11033539, Cpd. No. 9-8 | N-[2-(1-benzylpiperidin...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 503253BDBM503253(US11033539, Cpd. No. 22-10 | (2R)-N-[2-(1-benzylpi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

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