Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 9967
TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504290BDBM504290((4S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  34nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504287BDBM504287((4S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  39nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504291BDBM504291((4S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  39nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504284BDBM504284((6S)-3-[2,6-Difluoro-4-[2-(3-pyridyl)ethynyl]pheny...)
Affinity DataEC50:  43nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504283BDBM504283((4S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  51nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504286BDBM504286((4S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  51nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504243BDBM504243((6S)-3-[2,6-Difluoro-4-[2-(3-pyridyl)ethynyl]pheny...)
Affinity DataEC50:  52nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504289BDBM504289((4S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  54nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504211BDBM504211((8S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  58nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504255BDBM504255((6S)-3-[2,6-Difluoro-4-[2-(3-pyridyl)ethynyl]pheny...)
Affinity DataEC50:  61nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504280BDBM504280((5S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  65nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504281BDBM504281((5S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  65nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504288BDBM504288((4S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  75nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504279BDBM504279((5S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  76nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504282BDBM504282((4S)-3′-[2,6-Difluoro-4-[2-(3-pyridyl)ethyny...)
Affinity DataEC50:  88nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504273BDBM504273((5S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  94nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 504285BDBM504285((8S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  114nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent