Compile Data Set for Download or QSAR
maximum 50k data
Found 98 Enz. Inhib. hit(s) with all data for entry = 10061
TargetTumor necrosis factor(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511474(US11059789, Example 23 | US11691950, Example 23)
Affinity DataIC50:  4.5nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)
Affinity DataIC50:  9nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)
Affinity DataIC50:  11nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511480(US11059789, Example 40 | US11691950, Example 40)
Affinity DataIC50:  13nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)
Affinity DataIC50:  13nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)
Affinity DataIC50:  14nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511476(US11059789, Example 28 | US11691950, Example 28)
Affinity DataIC50:  15.5nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511481(US11059789, Example 25 | US11691950, Example 25)
Affinity DataIC50:  17nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511480(US11059789, Example 40 | US11691950, Example 40)
Affinity DataIC50:  19nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)
Affinity DataIC50:  21nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511481(US11059789, Example 25 | US11691950, Example 25)
Affinity DataIC50:  25nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511483(US11059789, Example 66 | US11691950, Example 66)
Affinity DataIC50:  26nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511486(US11059789, Example 19 | US11691950, Example 19)
Affinity DataIC50:  27nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)
Affinity DataIC50:  29nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)
Affinity DataIC50:  29nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511483(US11059789, Example 66 | US11691950, Example 66)
Affinity DataIC50:  36nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)
Affinity DataIC50:  51nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C delta type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)
Affinity DataIC50:  56nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511486(US11059789, Example 19 | US11691950, Example 19)
Affinity DataIC50:  58nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511480(US11059789, Example 40 | US11691950, Example 40)
Affinity DataIC50:  71nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511477(US11059789, Example 29 | US11691950, Example 29)
Affinity DataIC50:  71nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)
Affinity DataIC50:  81nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511468(US11059789, Example 12 | US11691950, Example 12)
Affinity DataIC50:  90.5nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)
Affinity DataIC50:  95nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511470(US11059789, Example 91 | US11691950, Example 91)
Affinity DataIC50:  102nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511483(US11059789, Example 66 | US11691950, Example 66)
Affinity DataIC50:  117nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511481(US11059789, Example 25 | US11691950, Example 25)
Affinity DataIC50:  138nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C delta type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)
Affinity DataIC50:  142nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511472(US11059789, Example 20 | US11691950, Example 20)
Affinity DataIC50:  144nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)
Affinity DataIC50:  145nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C delta type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511480(US11059789, Example 40 | US11691950, Example 40)
Affinity DataIC50:  152nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)
Affinity DataIC50:  154nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511481(US11059789, Example 25 | US11691950, Example 25)
Affinity DataIC50:  173nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511480(US11059789, Example 40 | US11691950, Example 40)
Affinity DataIC50:  190nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C delta type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511481(US11059789, Example 25 | US11691950, Example 25)
Affinity DataIC50:  225nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511475(US11059789, Example 26 | US11691950, Example 26)
Affinity DataIC50:  227nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511466(US11059789, Example 4 | US11691950, Example 4)
Affinity DataIC50:  230nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511480(US11059789, Example 40 | US11691950, Example 40)
Affinity DataIC50:  244nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511483(US11059789, Example 66 | US11691950, Example 66)
Affinity DataIC50:  282nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511471(US11059789, Example 90 | US11691950, Example 90)
Affinity DataIC50:  300nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)
Affinity DataIC50:  317nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)
Affinity DataIC50:  331nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511486(US11059789, Example 19 | US11691950, Example 19)
Affinity DataIC50:  332nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C delta type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511483(US11059789, Example 66 | US11691950, Example 66)
Affinity DataIC50:  357nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511467(US11059789, Example 11 | US11691950, Example 11)
Affinity DataIC50:  429nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511486(US11059789, Example 19 | US11691950, Example 19)
Affinity DataIC50:  436nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C delta type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)
Affinity DataIC50:  509nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511480(US11059789, Example 40 | US11691950, Example 40)
Affinity DataIC50:  523nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C delta type(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511486(US11059789, Example 19 | US11691950, Example 19)
Affinity DataIC50:  589nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM511469(US11059789, Example 14 | US11691950, Example 14)
Affinity DataIC50:  620nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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