Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 10066
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458816BDBM458816(N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-...)
Affinity DataIC50: 0.300nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458826BDBM458826(6-((1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)(ethyl...)
Affinity DataIC50: 0.800nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287068BDBM50287068(CHEMBL4172576 | US10759787, Example 30 | US1105981...)
Affinity DataIC50: 0.800nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458817BDBM458817(6-(Ethyl(1-(methylsulfonyl)piperidin-4-yl)amino)-N...)
Affinity DataIC50: 0.900nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 511685BDBM511685(5-Ethyl-6-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2...)
Affinity DataIC50: 1.20nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458802BDBM458802(5-Ethyl-6-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2...)
Affinity DataIC50: 1.70nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287277BDBM50287277(CHEMBL4170753 | US10759787, Example 18 | US1105981...)
Affinity DataIC50: 2.30nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287071BDBM50287071(CHEMBL4164687 | US10759787, Example 29 | US1105981...)
Affinity DataIC50: 2.70nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458824BDBM458824(6-((4,4-Difluorocyclohexyl)(ethyl)amino)-5-ethyl-N...)
Affinity DataIC50: 2.70nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458826BDBM458826(6-((1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)(ethyl...)
Affinity DataIC50: 2.70nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458818BDBM458818(6-((1-Acetylpiperidin-4-yl)(ethyl)amino)-N-((4-met...)
Affinity DataIC50: 2.80nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287125BDBM50287125(CHEMBL4170327 | US10759787, Example 19 | US1105981...)
Affinity DataIC50: 2.80nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458818BDBM458818(6-((1-Acetylpiperidin-4-yl)(ethyl)amino)-N-((4-met...)
Affinity DataIC50: 2.90nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458805BDBM458805(2-((Dimethylamino)methyl)-5-ethyl-6-(ethyl(tetrahy...)
Affinity DataIC50: 2.90nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287125BDBM50287125(CHEMBL4170327 | US10759787, Example 19 | US1105981...)
Affinity DataIC50: 2.90nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458817BDBM458817(6-(Ethyl(1-(methylsulfonyl)piperidin-4-yl)amino)-N...)
Affinity DataIC50: 3.20nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458828BDBM458828(6-(((1r,4r)-4-(Dimethylamino)cyclohexyl)(ethyl)ami...)
Affinity DataIC50: 3.40nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458797BDBM458797(2-((4,4-Difluoropiperidin-1-yl)methyl)-5-ethyl-6-(...)
Affinity DataIC50: 3.5nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458820BDBM458820(5-Ethyl-6-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2...)
Affinity DataIC50: 3.5nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458825BDBM458825(6-((3,3-Difluorocyclobutyl)(ethyl)amino)-5-ethyl-N...)
Affinity DataIC50: 4nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458787BDBM458787(N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 4nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287048BDBM50287048(CHEMBL4162499 | US10759787, Example 9 | US11059811...)
Affinity DataIC50: 4nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287277BDBM50287277(CHEMBL4170753 | US10759787, Example 18 | US1105981...)
Affinity DataIC50: 4nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458824BDBM458824(6-((4,4-Difluorocyclohexyl)(ethyl)amino)-5-ethyl-N...)
Affinity DataIC50: 4.5nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458816BDBM458816(N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-...)
Affinity DataIC50: 4.80nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287056BDBM50287056(CHEMBL4169598 | US10759787, Example 20 | US1105981...)
Affinity DataIC50: 5.60nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458803BDBM458803(N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 5.60nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287048BDBM50287048(CHEMBL4162499 | US10759787, Example 9 | US11059811...)
Affinity DataIC50: 5.70nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458787BDBM458787(N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 5.70nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287056BDBM50287056(CHEMBL4169598 | US10759787, Example 20 | US1105981...)
Affinity DataIC50: 5.90nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458798BDBM458798(5-Ethyl-6-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-N...)
Affinity DataIC50: 6.20nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287053BDBM50287053(CHEMBL4161444 | US10759787, Example 1 | US11059811...)
Affinity DataIC50: 6.40nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458815BDBM458815(5-Chloro-6-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-...)
Affinity DataIC50: 6.5nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458821BDBM458821(2-Cyclopropyl-6-((cyclopropylmethyl)(tetrahydro-2H...)
Affinity DataIC50: 6.80nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287307BDBM50287307(CHEMBL4176554 | US10759787, Example 6 | US11059811...)
Affinity DataIC50: 7.80nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458806BDBM458806(2-Cyclopentyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropy...)
Affinity DataIC50: 9.60nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458809BDBM458809(5-Ethyl-6-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-N...)
Affinity DataIC50: 9.90nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 50287072BDBM50287072(CHEMBL4159112 | US10759787, Example 12 | US1105981...)
Affinity DataIC50: 10nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458827BDBM458827(6-((Cyclopropylmethyl)(1-(2,2,2-trifluoroethyl)pip...)
Affinity DataIC50: 14nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458793BDBM458793(6-(Ethyl(tetrahydro-2H-pyran-4-yl)amino)-N-((4-met...)
Affinity DataIC50: 14nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458807BDBM458807(N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 16nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458808BDBM458808(N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 31nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [A677G](Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 458788BDBM458788(5-Ethyl-6-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-N...)
Affinity DataIC50: 38nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent