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Found 30 Enz. Inhib. hit(s) with all data for entry = 10098
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513956(US11059824, Compound loxoribine)
Affinity DataEC50:  3.22E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513989(US11059824, Compound 37)
Affinity DataEC50:  5.64E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513958(US11059824, Compound 2)
Affinity DataEC50:  2.98E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513959(US11059824, Compound 5)
Affinity DataEC50:  2.92E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513961(US11059824, Compound 6)
Affinity DataEC50:  8.35E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513962(US11059824, Compound 7)
Affinity DataEC50:  5.35E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513963(US11059824, Compound 8)
Affinity DataEC50:  4.13E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513964(US11059824, Compound 9)
Affinity DataEC50:  1.50E+4nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513965(US11059824, Compound 10)
Affinity DataEC50:  2.48E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513966(US11059824, Compound 11)
Affinity DataEC50:  2.49E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513968(US11059824, Compound 12)
Affinity DataEC50:  4.07E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513969(US11059824, Compound 13)
Affinity DataEC50:  1.51E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513970(US11059824, Compound 14)
Affinity DataEC50:  1.80E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513971(US11059824, Compound 15)
Affinity DataEC50: >5.00E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513972(US11059824, Compound 16)
Affinity DataEC50:  5.34E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513973(US11059824, Compound 17)
Affinity DataEC50:  3.37E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513974(US11059824, Compound 18)
Affinity DataEC50:  3.30E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513975(US11059824, Compound 19)
Affinity DataEC50:  4.91E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513976(US11059824, Compound 20)
Affinity DataEC50:  7.90E+4nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513977(US11059824, Compound 21)
Affinity DataEC50:  5.20E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513978(US11059824, Compound 22)
Affinity DataEC50:  5.67E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513981(US11059824, Compound 23)
Affinity DataEC50: >5.00E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513982(US11059824, Compound 26)
Affinity DataEC50:  5.19E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513983(US11059824, Compound 27)
Affinity DataEC50:  3.76E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513984(US11059824, Compound 28)
Affinity DataEC50:  4.70E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513985(US11059824, Compound 33)
Affinity DataEC50:  6.88E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513986(US11059824, Compound 34)
Affinity DataEC50:  5.12E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513987(US11059824, Compound 35)
Affinity DataEC50:  1.16E+6nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513988(US11059824, Compound 36)
Affinity DataEC50:  1.21E+6nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Primmune Therapeutics

US Patent
LigandPNGBDBM513957(US11059824, Compound 1)
Affinity DataEC50:  1.88E+5nMAssay Description:The engagement of TLRs by cognate ligands triggers downstream signaling cascades, leading to the activation of NF-κB and other transcription fac...More data for this Ligand-Target Pair
In DepthDetails US Patent