Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 10149
LigandChemical structure of BindingDB Monomer ID 516932BDBM516932(US11104675, Example 18a | US11104675, Example 18b)
Affinity DataIC50: 3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516935BDBM516935(US11104675, Example 20b)
Affinity DataIC50: 5nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516934BDBM516934(US11104675, Example 19b)
Affinity DataIC50: 12nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516921BDBM516921(US11104675, Example 12a | US11104675, Example 12b)
Affinity DataIC50: 20nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 497074BDBM497074(US11104675, Example 10b | US11001561, Compound 63 ...)
Affinity DataIC50: 28nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516917BDBM516917(US11104675, Example 9)
Affinity DataIC50: 45nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516929BDBM516929(US11104675, Example 16a | US11104675, Example 16b)
Affinity DataIC50: 92nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516906BDBM516906(US11104675, Example 2a | US11104675, Example 2b)
Affinity DataIC50: 122nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516927BDBM516927(US11104675, Example 15a | US11104675, Example 15b)
Affinity DataIC50: 148nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516915BDBM516915(US11104675, Example 7b)
Affinity DataIC50: 153nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516923BDBM516923(US11104675, Example 13a | US11104675, Example 13b)
Affinity DataIC50: 186nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516913BDBM516913(US11104675, Example 6)
Affinity DataIC50: 203nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 497007BDBM497007(US11104675, Example 3 | US11001561, Compound 4 | U...)
Affinity DataIC50: 310nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516916BDBM516916(US11104675, Example 8)
Affinity DataIC50: 360nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 497029BDBM497029(US11104675, Example 11 | US11001561, Compound 24 |...)
Affinity DataIC50: 366nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516911BDBM516911(US11104675, Example 4)
Affinity DataIC50: 480nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 497001BDBM497001(US11104675, Example 1 | US11001561, Compound 2 | U...)
Affinity DataIC50: 510nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516932BDBM516932(US11104675, Example 18a | US11104675, Example 18b)
Affinity DataIC50: 511nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516931BDBM516931(US11104675, Example 17)
Affinity DataIC50: 618nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516925BDBM516925(US11104675, Example 14a | US11104675, Example 14b)
Affinity DataIC50: 703nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516925BDBM516925(US11104675, Example 14a | US11104675, Example 14b)
Affinity DataIC50: 1.00E+3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516927BDBM516927(US11104675, Example 15a | US11104675, Example 15b)
Affinity DataIC50: 1.00E+3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516912BDBM516912(US11104675, Example 5)
Affinity DataIC50: 1.17E+3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 497074BDBM497074(US11104675, Example 10b | US11001561, Compound 63 ...)
Affinity DataIC50: 2.58E+3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516921BDBM516921(US11104675, Example 12a | US11104675, Example 12b)
Affinity DataIC50: 3.46E+3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516906BDBM516906(US11104675, Example 2a | US11104675, Example 2b)
Affinity DataIC50: 7.05E+3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516923BDBM516923(US11104675, Example 13a | US11104675, Example 13b)
Affinity DataIC50: 7.50E+3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516929BDBM516929(US11104675, Example 16a | US11104675, Example 16b)
Affinity DataIC50: 9.55E+3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 516914BDBM516914(US11104675, Example 7a)
Affinity DataIC50: 1.00E+4nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent