Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 10158
TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233168BDBM50233168(CHEMBL4085965 | US11124490, Compound 11)
Affinity DataIC50: 9.32nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233154BDBM50233154(CHEMBL4096134 | US11124490, Compound 10)
Affinity DataIC50: 31.5nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233173BDBM50233173(CHEMBL4094366 | US11124490, Compound 14)
Affinity DataIC50: 35.3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233166BDBM50233166(CHEMBL4060128 | US11124490, Compound 3g)
Affinity DataIC50: 40.1nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233155BDBM50233155(CHEMBL4080953 | US11124490, Compound 28b)
Affinity DataIC50: 55.5nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233157BDBM50233157(CHEMBL4097500 | US11124490, Compound 28a)
Affinity DataIC50: 66.9nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233170BDBM50233170(CHEMBL4073772 | US11124490, Compound 13)
Affinity DataIC50: 67.3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233171BDBM50233171(CHEMBL4099620 | US11124490, Compound 15)
Affinity DataIC50: 83.1nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233169BDBM50233169(CHEMBL4082022 | US11124490, Compound 3f)
Affinity DataIC50: 83.7nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233164BDBM50233164(CHEMBL4105201 | US11124490, Compound 29)
Affinity DataIC50: 100nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50187687BDBM50187687(CHEMBL3828733 | US11124490, Compound 918013)
Affinity DataIC50: 117nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233163BDBM50233163(CHEMBL4102111 | US11124490, Compound 12)
Affinity DataIC50: 121nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233160BDBM50233160(CHEMBL4071490 | US11124490, Compound 3h)
Affinity DataIC50: 190nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233168BDBM50233168(CHEMBL4085965 | US11124490, Compound 11)
Affinity DataIC50: 396nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233188BDBM50233188(CHEMBL4098521 | US11124490, Compound 3i)
Affinity DataIC50: 864nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233159BDBM50233159(CHEMBL4072723 | US11124490, Compound 19)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233167BDBM50233167(CHEMBL4091887 | US11124490, Compound 20)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233184BDBM50233184(CHEMBL4064138 | US11124490, Compound 22)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233186BDBM50233186(CHEMBL4070002 | US11124490, Compound 23)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233177BDBM50233177(CHEMBL4070890 | US11124490, Compound 3d)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233185BDBM50233185(CHEMBL4090985 | US11124490, Compound 25)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233183BDBM50233183(CHEMBL4091756 | US11124490, Compound 3e)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233156BDBM50233156(CHEMBL4070321 | US11124490, Compound 26a)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 517730BDBM517730(US11124490, Compound 4)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233154BDBM50233154(CHEMBL4096134 | US11124490, Compound 10)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50233168BDBM50233168(CHEMBL4085965 | US11124490, Compound 11)
Affinity DataIC50: 1.03E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent