Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 10209
TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520269BDBM520269(US11130750, Example 1)
Affinity DataIC50: 500nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 78934BDBM78934(MLS001056800 | Mibefradil dihydrochloride hydrate ...)
Affinity DataIC50: 720nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 78934BDBM78934(MLS001056800 | Mibefradil dihydrochloride hydrate ...)
Affinity DataIC50: 720nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520274BDBM520274(US11130750, Example 6)
Affinity DataIC50: 2.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520270BDBM520270(US11130750, Example 2)
Affinity DataIC50: 3.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520281BDBM520281(US11130750, Example 21A | (4S)-3-(2-((3-(4,7-Dimet...)
Affinity DataIC50: 3.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520282BDBM520282(US11130750, Example 21B)
Affinity DataIC50: 3.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520271BDBM520271(US11130750, Example 3)
Affinity DataIC50: 5.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520273BDBM520273(US11130750, Example 5)
Affinity DataIC50: 6.00E+3nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520280BDBM520280(US11130750, Example 16)
Affinity DataIC50: 7.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520278BDBM520278(US11130750, Example 12)
Affinity DataIC50: 7.90E+3nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520276BDBM520276(US11130750, Example 10)
Affinity DataIC50: 9.00E+3nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520277BDBM520277(US11130750, Example 11)
Affinity DataIC50: 1.20E+4nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520274BDBM520274(US11130750, Example 6)
Affinity DataIC50: 1.30E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520281BDBM520281(US11130750, Example 21A | (4S)-3-(2-((3-(4,7-Dimet...)
Affinity DataIC50: 1.50E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520282BDBM520282(US11130750, Example 21B)
Affinity DataIC50: 1.50E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520270BDBM520270(US11130750, Example 2)
Affinity DataIC50: 1.60E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520279BDBM520279(US11130750, Example 15)
Affinity DataIC50: 1.80E+4nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520269BDBM520269(US11130750, Example 1)
Affinity DataIC50: 1.90E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520280BDBM520280(US11130750, Example 16)
Affinity DataIC50: 1.90E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520273BDBM520273(US11130750, Example 5)
Affinity DataIC50: 1.90E+4nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520272BDBM520272(US11130750, Example 4)
Affinity DataIC50: 2.00E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520272BDBM520272(US11130750, Example 4)
Affinity DataIC50: 2.40E+4nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520271BDBM520271(US11130750, Example 3)
Affinity DataIC50: 2.50E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520275BDBM520275(US11130750, Example 9)
Affinity DataIC50: 2.60E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520279BDBM520279(US11130750, Example 15)
Affinity DataIC50: 2.70E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandChemical structure of BindingDB Monomer ID 520277BDBM520277(US11130750, Example 11)
Affinity DataIC50: 3.00E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent