Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 10260
TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523849BDBM523849(US11136320, Compound 8)
Affinity DataIC50: 0.420nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523841BDBM523841(US11136320, Compound 4)
Affinity DataIC50: 1.40nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523847BDBM523847(US11136320, Compound 7)
Affinity DataIC50: 1.5nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523839BDBM523839(US11136320, Compound 1)
Affinity DataIC50: 1.5nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523861BDBM523861(US11136320, Compound 56)
Affinity DataIC50: 1.60nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523846BDBM523846(US11136320, Compound 64)
Affinity DataIC50: 1.60nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523844BDBM523844(US11136320, Compound 62)
Affinity DataIC50: 1.70nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523856BDBM523856(US11136320, Compound 75)
Affinity DataIC50: 1.80nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523843BDBM523843(US11136320, Compound 5 | N-(5-cyano-4-((tetrahydro...)
Affinity DataIC50: 2nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523851BDBM523851(US11136320, Compound 9)
Affinity DataIC50: 2nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523852BDBM523852(US11136320, Compound 72)
Affinity DataIC50: 2nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523860BDBM523860(US11136320, Compound 83)
Affinity DataIC50: 2.10nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523845BDBM523845(US11136320, Compound 6)
Affinity DataIC50: 2.10nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523863BDBM523863(US11136320, Compound 58)
Affinity DataIC50: 2.10nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523848BDBM523848(US11136320, Compound 69)
Affinity DataIC50: 2.10nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523840BDBM523840(US11136320, Compound 59)
Affinity DataIC50: 2.10nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523858BDBM523858(US11136320, Compound 76)
Affinity DataIC50: 2.10nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523853BDBM523853(US11136320, Compound 16)
Affinity DataIC50: 2.20nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523854BDBM523854(US11136320, Compound 73)
Affinity DataIC50: 2.30nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523850BDBM523850(US11136320, Compound 71)
Affinity DataIC50: 2.40nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523857BDBM523857(US11136320, Compound 27)
Affinity DataIC50: 2.40nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 209325BDBM209325(US9266883, 83 | US11136320, Reference Compound)
Affinity DataIC50: 2.90nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523859BDBM523859(US11136320, Compound 55)
Affinity DataIC50: 3nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523842BDBM523842(US11136320, Compound 60)
Affinity DataIC50: 3nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Jacobio Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 523855BDBM523855(US11136320, Compound 20)
Affinity DataIC50: 4.40nMAssay Description:The FGFR4 kinase inhibition of compounds was tested by using mobility shift assay in this experiment, and the rate of FGFR4 kinase inhibition of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent