Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 10261
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523870BDBM523870(US11136324, Example 10 | 5-(4-Cyclopropyl-1H-imida...)
Affinity DataIC50: 1nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523874BDBM523874(US11136324, Example 15 | (R)-5-(4-(tert-Butyl)-1H-...)
Affinity DataIC50: 1.40nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523868BDBM523868(US11136324, Example 8 | (R)-5-(4-Cyclopropyl-1H-im...)
Affinity DataIC50: 1.80nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523892BDBM523892(US11136324, Example 55 | (R)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 1.90nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523896BDBM523896(US11136324, Example 61 | 5-(4-Cyclopropyl-1H-imida...)
Affinity DataIC50: 1.90nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523884BDBM523884(US11136324, Example 40 | (S)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 1.90nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523886BDBM523886(US11136324, Example 43 | (S)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 1.90nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523872BDBM523872(US11136324, Example 13 | (R)-2-Fluoro-5-(4-isoprop...)
Affinity DataIC50: 2.70nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523894BDBM523894(US11136324, Example 59 | (R)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 2.90nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523897BDBM523897(US11136324, Example 62 | N-(6-(6′,7′-D...)
Affinity DataIC50: 3nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523882BDBM523882(US11136324, Example 37 | (S)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 3.5nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523887BDBM523887(US11136324, Example 44 | 5-(4-Cyclopropyl-1H-imida...)
Affinity DataIC50: 3.60nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523875BDBM523875(US11136324, Example 16 | (S)-5-(4-(tert-Butyl)-1H-...)
Affinity DataIC50: 4.10nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523883BDBM523883(US11136324, Example 38 | (S)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 4.10nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523890BDBM523890(US11136324, Example 51 | (S)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 4.90nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523878BDBM523878(US11136324, Example 32 | 5-(4-Cyclopropyl-1H-imida...)
Affinity DataIC50: 4.90nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523893BDBM523893(US11136324, Example 56 | (S)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 5nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523869BDBM523869(US11136324, Example 9 | (S)-5-(4-Cyclopropyl-1H-im...)
Affinity DataIC50: 5nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523880BDBM523880(US11136324, Example 34 | (R)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 5.20nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523899BDBM523899(US11136324, Example 64 | 6-(4-Cyclopropyl-1H-imida...)
Affinity DataIC50: 5.5nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 504319BDBM504319(WX001 | US11040968, Example 001 | US11136324, Exam...)
Affinity DataIC50: 6nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523888BDBM523888(US11136324, Example 48 | (S) N-(6-(5-(Cyanomethyl)...)
Affinity DataIC50: 6.10nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523895BDBM523895(US11136324, Example 60 | (S)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 6.60nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523879BDBM523879(US11136324, Example 33 | 5-(4-Cyclopropyl-1H-imida...)
Affinity DataIC50: 7.20nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523885BDBM523885(US11136324, Example 41 | 5-(4-Cyclopropyl-1H-imida...)
Affinity DataIC50: 7.70nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523891BDBM523891(US11136324, Example 53 | (R)-2-Chloro-5-(4-cyclopr...)
Affinity DataIC50: 8.20nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523898BDBM523898(US11136324, Example 63 | 6-(4-Cyclopropyl-1H-imida...)
Affinity DataIC50: 8.40nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523873BDBM523873(US11136324, Example 14 | (S)-2-Fluoro-5-(4-isoprop...)
Affinity DataIC50: 9nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523881BDBM523881(US11136324, Example 36 | 5-(4-Cyclopropyl-1H-imida...)
Affinity DataIC50: 9.10nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523864BDBM523864(US11136324, Example 2 | 5-(4-Cyclopropyl-1H-imidaz...)
Affinity DataIC50: 9.30nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523900BDBM523900(US11136324, Example 65 | (S)-6-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 9.40nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523889BDBM523889(US11136324, Example 50 | (S)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 9.60nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523871BDBM523871(US11136324, Example 11 | (S)-5-(4-Cyclopropyl-1H-i...)
Affinity DataIC50: 10.6nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523877BDBM523877(US11136324, Example 31 | N-(6-(5′H,7′H...)
Affinity DataIC50: 10.9nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523876BDBM523876(US11136324, Example 30 | 5-(4-Cyclopropyl-1H-imida...)
Affinity DataIC50: 11.4nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 504320BDBM504320(WX002 | US11040968, Example 002 | US11136324, Exam...)
Affinity DataIC50: 13.4nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523867BDBM523867(US11136324, Example 7 | 4-(4-Cyclopropyl-1H-imidaz...)
Affinity DataIC50: 19.6nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 523866BDBM523866(US11136324, Example 4 | 5-(4-Cyclopropyl-1H-imidaz...)
Affinity DataIC50: 47.8nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent