Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 10268
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524064(US11136336, Example 15)
Affinity DataIC50: 9nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524060(US11136336, Example 11)
Affinity DataIC50: 10nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524041(US11136336, Example 1 | 3-({3-[(2S)-2-(4-chlorophe...)
Affinity DataIC50: 13nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524067(US11136336, WO2017/060488 Example 72 | 7-Bromo-3-(...)
Affinity DataIC50: 14nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524061(US11136336, Example 12)
Affinity DataIC50: 15nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524065(US11136336, Example 16)
Affinity DataIC50: 16nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524052(US11136336, Example 3)
Affinity DataIC50: 19nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524051(US11136336, Example 2)
Affinity DataIC50: 20nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524063(US11136336, Example 14)
Affinity DataIC50: 33nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524053(US11136336, Example 4)
Affinity DataIC50: 33nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524056(US11136336, Example 7)
Affinity DataIC50: 34nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524068(US11136336, WO2017/060488 Example 73 | 3-((3-(2-(4...)
Affinity DataIC50: 35nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524066(US11136336, WO2017/060488 Example 53 | 1-({3-[2-(4...)
Affinity DataIC50: 36nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524062(US11136336, Example 13)
Affinity DataIC50: 37nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524070(US11136336, WO2017/060488 Example 90 | 5-((3-(2-(4...)
Affinity DataIC50: 41nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524054(US11136336, Example 5)
Affinity DataIC50: 48nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524055(US11136336, Example 6)
Affinity DataIC50: 48nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50157702(CHEMBL3786639 | US11136336, Med. Chem. 2016, 59, 2...)
Affinity DataIC50: 52nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524059(US11136336, Example 10)
Affinity DataIC50: 52nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524057(US11136336, Example 8)
Affinity DataIC50: 56nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524069(US11136336, WO2017/060488 Example 86 | 1-((3-(2-(4...)
Affinity DataIC50: 67nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM524058(US11136336, Example 9)
Affinity DataIC50: 78nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent