Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 10311
TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526970BDBM526970(5-(3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin 7-...)
Affinity DataEC50:  13nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526969BDBM526969(5-(1-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-5- ...)
Affinity DataEC50:  15nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526968BDBM526968(5-(3-(2,3-difluorophenyl)imidazo[1,2- b]pyridazin-...)
Affinity DataEC50:  15nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526967BDBM526967(5-(3-chloro-1-(2,3-difluorophenyl)imidazo[1,5- a]p...)
Affinity DataEC50:  19nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526966BDBM526966(N-(4-fluorophenyl)-5-(3-(pyridin-3- yl)imidazo[1,2...)
Affinity DataEC50:  21nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526965BDBM526965(5-(3-(2,3-difluorophenyl)imidazo[1,2- b]pyridazin-...)
Affinity DataEC50:  25nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526964BDBM526964(5-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  37nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526963BDBM526963(5-(3-(2,3-difluorophenyl)-2- (hydroxymethyl)imidaz...)
Affinity DataEC50:  40nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526962BDBM526962(5-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  45nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526961BDBM526961(N-(4-fluorophenyl)-5-(3-(5-fluoropyridin-3- yl)imi...)
Affinity DataEC50:  58nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526960BDBM526960(N-(4-fluorophenyl)-5-(3-(pyridin-3- yl)imidazo[1,2...)
Affinity DataEC50:  59nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526959BDBM526959(6-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  64nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526958BDBM526958(N-(4-fluorophenyl)-5-(3-(2- fluorophenyl)imidazo[1...)
Affinity DataEC50:  73nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526957BDBM526957(N-(4-fluorophenyl)-5-(3-(2-fluoropyridin-3- yl)imi...)
Affinity DataEC50:  74nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526955BDBM526955(5-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  89nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526956BDBM526956(N-(4-fluorophenyl)-5-(2-(hydroxymethyl)-3- (pyridi...)
Affinity DataEC50:  89nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526954BDBM526954(N-(4-fluorophenyl)-5-(3-(3- fluorophenyl)imidazo[1...)
Affinity DataEC50:  146nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526953BDBM526953(N-(4-fluorophenyl)-5-(2-methyl-3-(pyridin-3- yl)im...)
Affinity DataEC50:  165nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526951BDBM526951(6-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  168nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526952BDBM526952(N-(4-fluorophenyl)-2-methyl-5-(3- phenylimidazo[1,...)
Affinity DataEC50:  168nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526950BDBM526950(2-chloro-N-(4-fluorophenyl)-5-(2- (hydroxymethyl)-...)
Affinity DataEC50:  272nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526949BDBM526949(5-(3-(2,3-difluorophenyl)-2- (hydroxymethyl)imidaz...)
Affinity DataEC50:  372nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526948BDBM526948(5-(3-(4-cyanopyridin-2-yl)imidazo[1,5-a]pyridin- 8...)
Affinity DataEC50:  395nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526945BDBM526945(US11186579, Example 12 | 5-(3-(2,3-difluorophenyl)...)
Affinity DataEC50:  403nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526946BDBM526946(5-(3-(2,3-difluorophenyl)-2-methylimidazo[1,2- a]p...)
Affinity DataEC50:  436nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526945BDBM526945(US11186579, Example 12 | 5-(3-(2,3-difluorophenyl)...)
Affinity DataEC50:  441nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526944BDBM526944(N-(4-fluorophenyl)-5-(3-(2-methylpyridin-3- yl)imi...)
Affinity DataEC50:  535nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526971BDBM526971(2-(5-(3-(2,3-difluorophenyl)imidazo[1,2- a]pyridin...)
Affinity DataEC50:  713nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526943BDBM526943(2-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  945nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526942BDBM526942(5-(2-(aminomethyl)-3-(2,3- difluorophenyl)imidazo[...)
Affinity DataEC50:  1.01E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526941BDBM526941(N-(4-fluorophenyl)-5-(3-(pyridin-4- yl)imidazo[1,2...)
Affinity DataEC50:  1.42E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526940BDBM526940(N-(4-fluorophenyl)-2-methyl-5-(3-(2- methylpyridin...)
Affinity DataEC50:  1.70E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526939BDBM526939(N-(4-fluorophenyl)-5-(3-(6-methylpyridin-3- yl)imi...)
Affinity DataEC50:  2.23E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526938BDBM526938(2-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  2.39E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526937BDBM526937(N-(4-fluorophenyl)-5-(3-(5-fluoropyridin-3-yl)-2- ...)
Affinity DataEC50:  3.61E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 526936BDBM526936(5-(3-(2,3-difluorophenyl)-2-((2- methoxyethoxy)met...)
Affinity DataEC50:  8.68E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent