Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 10311
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526936(5-(3-(2,3-difluorophenyl)-2-((2- methoxyethoxy)met...)
Affinity DataEC50:  8.68E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526971(2-(5-(3-(2,3-difluorophenyl)imidazo[1,2- a]pyridin...)
Affinity DataEC50:  713nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526938(2-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  2.39E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526939(N-(4-fluorophenyl)-5-(3-(6-methylpyridin-3- yl)imi...)
Affinity DataEC50:  2.23E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526940(N-(4-fluorophenyl)-2-methyl-5-(3-(2- methylpyridin...)
Affinity DataEC50:  1.70E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526941(N-(4-fluorophenyl)-5-(3-(pyridin-4- yl)imidazo[1,2...)
Affinity DataEC50:  1.42E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526942(5-(2-(aminomethyl)-3-(2,3- difluorophenyl)imidazo[...)
Affinity DataEC50:  1.01E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526943(2-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  945nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526944(N-(4-fluorophenyl)-5-(3-(2-methylpyridin-3- yl)imi...)
Affinity DataEC50:  535nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526945(5-(3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin- 7...)
Affinity DataEC50:  441nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526946(5-(3-(2,3-difluorophenyl)-2-methylimidazo[1,2- a]p...)
Affinity DataEC50:  436nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526945(5-(3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin- 7...)
Affinity DataEC50:  403nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526948(5-(3-(4-cyanopyridin-2-yl)imidazo[1,5-a]pyridin- 8...)
Affinity DataEC50:  395nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526949(5-(3-(2,3-difluorophenyl)-2- (hydroxymethyl)imidaz...)
Affinity DataEC50:  372nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526950(2-chloro-N-(4-fluorophenyl)-5-(2- (hydroxymethyl)-...)
Affinity DataEC50:  272nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526951(6-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  168nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526952(N-(4-fluorophenyl)-2-methyl-5-(3- phenylimidazo[1,...)
Affinity DataEC50:  168nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526953(N-(4-fluorophenyl)-5-(2-methyl-3-(pyridin-3- yl)im...)
Affinity DataEC50:  165nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526954(N-(4-fluorophenyl)-5-(3-(3- fluorophenyl)imidazo[1...)
Affinity DataEC50:  146nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526955(5-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  89nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526956(N-(4-fluorophenyl)-5-(2-(hydroxymethyl)-3- (pyridi...)
Affinity DataEC50:  89nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526957(N-(4-fluorophenyl)-5-(3-(2-fluoropyridin-3- yl)imi...)
Affinity DataEC50:  74nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526958(N-(4-fluorophenyl)-5-(3-(2- fluorophenyl)imidazo[1...)
Affinity DataEC50:  73nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526959(6-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  64nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526960(N-(4-fluorophenyl)-5-(3-(pyridin-3- yl)imidazo[1,2...)
Affinity DataEC50:  59nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526961(N-(4-fluorophenyl)-5-(3-(5-fluoropyridin-3- yl)imi...)
Affinity DataEC50:  58nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526962(5-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  45nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526963(5-(3-(2,3-difluorophenyl)-2- (hydroxymethyl)imidaz...)
Affinity DataEC50:  40nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526964(5-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  37nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526965(5-(3-(2,3-difluorophenyl)imidazo[1,2- b]pyridazin-...)
Affinity DataEC50:  25nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526966(N-(4-fluorophenyl)-5-(3-(pyridin-3- yl)imidazo[1,2...)
Affinity DataEC50:  21nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526967(5-(3-chloro-1-(2,3-difluorophenyl)imidazo[1,5- a]p...)
Affinity DataEC50:  19nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526968(5-(3-(2,3-difluorophenyl)imidazo[1,2- b]pyridazin-...)
Affinity DataEC50:  15nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526969(5-(1-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-5- ...)
Affinity DataEC50:  15nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526970(5-(3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin 7-...)
Affinity DataEC50:  13nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526937(N-(4-fluorophenyl)-5-(3-(5-fluoropyridin-3-yl)-2- ...)
Affinity DataEC50:  3.61E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent