Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 10484
TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539995((E)-2-(4-(3-(2,7-dimethoxy-quinolin-3-yl)-3-oxo-1-...)
Affinity DataEC50:  1.33nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539997((E)-2-(4-(3-(2,6-dimethoxy-quinolin-3-yl)-3-oxo-1-...)
Affinity DataEC50:  5.40nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539994((E)-2-(4-(3-(2-chloro-7-methoxy-quinolin-3-yl)-3-o...)
Affinity DataEC50:  8.62nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539944((E)-2-(4-(3-(2-methoxyquinolin-3-yl)-3-oxo-1-prope...)
Affinity DataEC50:  28.3nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539945((E)-2-(4-(3-(2-(2-methoxyethoxy) quinolin-3-yl)-3-...)
Affinity DataEC50:  52.8nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539987((E)-2-(4-(3-(2-(1-pyrrolidinyl) quinolin-3-yl)-3-o...)
Affinity DataEC50:  77nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539993((E)-2-(4-(3-(2-methylthioquinolin-3-yl)-3-oxo-1-pr...)
Affinity DataEC50:  123nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539907((E)-2-(4-(3-(2-chloroquinolin-3-yl)-3-oxo-1-propen...)
Affinity DataEC50:  278nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539985((E)-2-(4-(3-(2-dimethylaminoquinolin-3-yl)-3-oxo-1...)
Affinity DataEC50:  307nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539945((E)-2-(4-(3-(2-(2-methoxyethoxy) quinolin-3-yl)-3-...)
Affinity DataEC50:  374nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539996((E)-2-(4-(3-(2-chloro-6-methoxy-quinolin-3-yl)-3-o...)
Affinity DataEC50:  460nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539944((E)-2-(4-(3-(2-methoxyquinolin-3-yl)-3-oxo-1-prope...)
Affinity DataEC50:  556nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539992((E)-2-(4-(3-(2-(morpholin-4-yl) quinolin-3-yl)-3-o...)
Affinity DataEC50:  585nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539997((E)-2-(4-(3-(2,6-dimethoxy-quinolin-3-yl)-3-oxo-1-...)
Affinity DataEC50:  675nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539983((E)-2-(4-(3-(2-trifluoromethylquinolin-3-yl)-3-oxo...)
Affinity DataEC50:  692nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539946((E)-2-(4-(3-(2-methylquinolin-3-yl)-3-oxo-1-propen...)
Affinity DataEC50:  752nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539995((E)-2-(4-(3-(2,7-dimethoxy-quinolin-3-yl)-3-oxo-1-...)
Affinity DataEC50:  796nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539994((E)-2-(4-(3-(2-chloro-7-methoxy-quinolin-3-yl)-3-o...)
Affinity DataEC50:  810nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539863((E)-2-(4-(3-(benzo [b] thien-2-yl)-3-oxo-1-propen-...)
Affinity DataEC50:  1.21E+3nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539864((E)-2-(4-(3-(quinolin-3-yl)-3-oxo-1-propen-1-yl)-2...)
Affinity DataEC50:  1.93E+3nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539987((E)-2-(4-(3-(2-(1-pyrrolidinyl) quinolin-3-yl)-3-o...)
Affinity DataEC50:  2.51E+3nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539907((E)-2-(4-(3-(2-chloroquinolin-3-yl)-3-oxo-1-propen...)
Affinity DataEC50:  3.44E+3nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539992((E)-2-(4-(3-(2-(morpholin-4-yl) quinolin-3-yl)-3-o...)
Affinity DataEC50:  4.43E+3nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539863((E)-2-(4-(3-(benzo [b] thien-2-yl)-3-oxo-1-propen-...)
Affinity DataEC50:  6.13E+3nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539985((E)-2-(4-(3-(2-dimethylaminoquinolin-3-yl)-3-oxo-1...)
Affinity DataEC50:  6.70E+3nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539863((E)-2-(4-(3-(benzo [b] thien-2-yl)-3-oxo-1-propen-...)
Affinity DataIC50: 8.24E+3nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539907((E)-2-(4-(3-(2-chloroquinolin-3-yl)-3-oxo-1-propen...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539864((E)-2-(4-(3-(quinolin-3-yl)-3-oxo-1-propen-1-yl)-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539945((E)-2-(4-(3-(2-(2-methoxyethoxy) quinolin-3-yl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539944((E)-2-(4-(3-(2-methoxyquinolin-3-yl)-3-oxo-1-prope...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539985((E)-2-(4-(3-(2-dimethylaminoquinolin-3-yl)-3-oxo-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539983((E)-2-(4-(3-(2-trifluoromethylquinolin-3-yl)-3-oxo...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539993((E)-2-(4-(3-(2-methylthioquinolin-3-yl)-3-oxo-1-pr...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539987((E)-2-(4-(3-(2-(1-pyrrolidinyl) quinolin-3-yl)-3-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539995((E)-2-(4-(3-(2,7-dimethoxy-quinolin-3-yl)-3-oxo-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539994((E)-2-(4-(3-(2-chloro-7-methoxy-quinolin-3-yl)-3-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM539997((E)-2-(4-(3-(2,6-dimethoxy-quinolin-3-yl)-3-oxo-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the compound on hERG potassium ion channel was tested by Predictor hERG fluorescence polarization. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent