Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 10494
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541356(US11267803, Example 4)
Affinity DataIC50:  5.62nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541388(US11267803, Example 36)
Affinity DataIC50:  6.65nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541357(US11267803, Example 5)
Affinity DataIC50:  9.08nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541363(US11267803, Example 11)
Affinity DataIC50:  9.82nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541389(US11267803, Example 37)
Affinity DataIC50:  10.4nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541400(US11267803, Example 48)
Affinity DataIC50:  11nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541360(US11267803, Example 8)
Affinity DataIC50:  12.5nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541376(US11267803, Example 24)
Affinity DataIC50:  13.8nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541366(US11267803, Example 14)
Affinity DataIC50:  15.6nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541365(US11267803, Example 13)
Affinity DataIC50:  17.2nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541362(US11267803, Example 10)
Affinity DataIC50:  18.1nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541369(US11267803, Example 17)
Affinity DataIC50:  20.1nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541378(US11267803, Example 26)
Affinity DataIC50:  21.6nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541396(US11267803, Example 44)
Affinity DataIC50:  22.3nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541370(US11267803, Example 18)
Affinity DataIC50:  24.4nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541392(US11267803, Example 40)
Affinity DataIC50:  25.2nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541391(US11267803, Example 39)
Affinity DataIC50:  30.5nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541377(US11267803, Example 25)
Affinity DataIC50:  36.8nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541379(US11267803, Example 27)
Affinity DataIC50:  37.4nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541397(US11267803, Example 45)
Affinity DataIC50:  38.5nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541374(US11267803, Example 22)
Affinity DataIC50:  40.3nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541367(US11267803, Example 15)
Affinity DataIC50:  46nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541355(US11267803, Example 3)
Affinity DataIC50:  47.2nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541380(US11267803, Example 28)
Affinity DataIC50:  55.3nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541375(US11267803, Example 23)
Affinity DataIC50:  59.6nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541381(US11267803, Example 29)
Affinity DataIC50:  63.1nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541393(US11267803, Example 41)
Affinity DataIC50:  68nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541399(US11267803, Example 47)
Affinity DataIC50:  78.2nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541364(US11267803, Example 12)
Affinity DataIC50:  81.1nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541372(US11267803, Example 20)
Affinity DataIC50:  90.1nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541385(US11267803, Example 33)
Affinity DataIC50:  110nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541359(US11267803, Example 7)
Affinity DataIC50:  138nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541373(US11267803, Example 21)
Affinity DataIC50:  142nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541383(US11267803, Example 31)
Affinity DataIC50:  144nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541384(US11267803, Example 32)
Affinity DataIC50:  146nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541368(US11267803, Example 16)
Affinity DataIC50:  155nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541371(US11267803, Example 19)
Affinity DataIC50:  157nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541398(US11267803, Example 46)
Affinity DataIC50:  181nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541361(US11267803, Example 9)
Affinity DataIC50:  199nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541387(US11267803, Example 35)
Affinity DataIC50:  223nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541353(US11267803, Example 1)
Affinity DataIC50:  261nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541382(US11267803, Example 30)
Affinity DataIC50:  303nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541390(US11267803, Example 38)
Affinity DataIC50:  523nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541394(US11267803, Example 42)
Affinity DataIC50:  606nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541386(US11267803, Example 34)
Affinity DataIC50:  620nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541358(US11267803, Example 6)
Affinity DataIC50:  675nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541395(US11267803, Example 43)
Affinity DataIC50:  1.18E+3nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Orion Ophthalmology

US Patent
LigandPNGBDBM541354(US11267803, Example 2)
Affinity DataIC50:  2.91E+3nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent