Compile Data Set for Download or QSAR
Report error Found 379 Enz. Inhib. hit(s) with all data for entry = 10506
TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542405(US11274090, Example 138 Isomer 2)
Affinity DataIC50: 6.08nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542425(US11274090, Example 147 Isomer 2)
Affinity DataIC50: 6.16nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542280(US11274090, Example 91 Isomer 2)
Affinity DataIC50: 6.40nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542300(US11274090, Example 98 Isomer 2)
Affinity DataIC50: 6.59nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542423(US11274090, Example 146 Isomer 2)
Affinity DataIC50: 7.76nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542145(US11274090, Example 33 Isomer 4)
Affinity DataIC50: 8.30nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542403(US11274090, Example 137 Isomer 2)
Affinity DataIC50: 8.62nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542322(US11274090, Example 104 Isomer 2)
Affinity DataIC50: 9.10nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542397(US11274090, Example 135 Isomer 2)
Affinity DataIC50: 9.30nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542342(US11274090, Example 111 Isomer 2)
Affinity DataIC50: 9.40nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542276(US11274090, Example 90 Isomer 2)
Affinity DataIC50: 9.60nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542346(US11274090, Example 113 Isomer 2)
Affinity DataIC50: 10.2nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542162(US11274090, Example 41 Isomer 1)
Affinity DataIC50: 10.3nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542348(US11274090, Example 114 Isomer 2)
Affinity DataIC50: 10.5nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542366(US11274090, Example 124 Isomer 1)
Affinity DataIC50: 11nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542284(US11274090, Example 92 Isomer 2)
Affinity DataIC50: 11.5nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542259(US11274090, Example 82 Isomer 4)
Affinity DataIC50: 11.6nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542391(US11274090, Example 132 Isomer 2)
Affinity DataIC50: 13.3nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542113(US11274090, Example 20 Isomer 4 | US11274090, Exam...)
Affinity DataIC50: 13.7nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542387(US11274090, Example 130 Isomer 2)
Affinity DataIC50: 14nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542318(US11274090, Example 103 Isomer 2)
Affinity DataIC50: 14.3nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542393(US11274090, Example 133 Isomer 2)
Affinity DataIC50: 14.4nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542184(US11274090, Example 51 Isomer 1)
Affinity DataIC50: 15nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542265(US11274090, Example 84 Isomer 2)
Affinity DataIC50: 16.2nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542326(US11274090, Example 105 Isomer 2)
Affinity DataIC50: 16.4nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542311(US11274090, Example 101 Isomer 1)
Affinity DataIC50: 16.9nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542308(US11274090, Example 100 Isomer 2)
Affinity DataIC50: 16.9nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542370(US11274090, Example 125 Isomer 3)
Affinity DataIC50: 17.4nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542158(US11274090, Example 39 Isomer 3)
Affinity DataIC50: 17.7nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542139(US11274090, Example 32 Isomer 2)
Affinity DataIC50: 18.8nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542429(US11274090, Example 149 Isomer 4 | US11274090, Exa...)
Affinity DataIC50: 19nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542196(US11274090, Example 55 Isomer 1)
Affinity DataIC50: 19nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542118(US11274090, Example 22 Isomer 1)
Affinity DataIC50: 19.4nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542087(US11274090, Example 8 Isomer 4)
Affinity DataIC50: 19.6nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542371(US11274090, Example 125 Isomer 4)
Affinity DataIC50: 19.6nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542385(US11274090, Example 129 Isomer 2)
Affinity DataIC50: 20.2nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542263(US11274090, Example 83 Isomer 4)
Affinity DataIC50: 20.6nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542076(US11274090, Example 6 Isomer 4)
Affinity DataIC50: 20.9nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542372(US11274090, Example 126 Isomer 1)
Affinity DataIC50: 21.1nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542415(US11274090, Example 143 Isomer 2)
Affinity DataIC50: 21.2nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542379(US11274090, Example 127 Isomer 4)
Affinity DataIC50: 21.9nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542375(US11274090, Example 126 Isomer 4)
Affinity DataIC50: 22nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542132(US11274090, Example 29 Isomer 1)
Affinity DataIC50: 22.9nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542332(US11274090, Example 108 Isomer 2)
Affinity DataIC50: 23.7nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542193(US11274090, Example 54 Isomer 2)
Affinity DataIC50: 23.9nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542175(US11274090, Example 47 Isomer 2)
Affinity DataIC50: 24.2nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542383(US11274090, Example 128 Isomer 4)
Affinity DataIC50: 24.9nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542328(US11274090, Example 106 Isomer 2)
Affinity DataIC50: 25.5nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542170(US11274090, Example 45 Isomer 1)
Affinity DataIC50: 26nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542077(US11274090, Example 7 Isomer 1)
Affinity DataIC50: 26nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

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