Compile Data Set for Download or QSAR
Report error Found 442 Enz. Inhib. hit(s) with all data for entry = 10513
TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543064BDBM543064(3-(4-{[2-methoxy-5- (trifluoromethyl)phenyl]sulfam...)
Affinity DataIC50: 0.100nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543083BDBM543083(3-(pyridin-3-ylmethyl)-1-{4-[(5,6,7,8- tetrahydron...)
Affinity DataIC50: 0.300nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543116BDBM543116(3-{4-[(2-chloro-5- methylphenyl)sulfamoyl]phenyl}-...)
Affinity DataIC50: 0.300nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543293BDBM543293(1-[4-(1H-indole-7-sulfonyl)phenyl]-3-(pyridin- 3-y...)
Affinity DataIC50: 0.5nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543060BDBM543060(3-(4-{[2- (difluoromethoxy)phenyl]sulfamoyl}phenyl...)
Affinity DataIC50: 0.600nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543328BDBM543328(3-(4-{[3-fluoro-5-(trifluoromethyl)benzene]sulfony...)
Affinity DataIC50: 0.700nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543036BDBM543036(1-[4-(dibenzylsulfamoyl)phenyl]-3-(pyridin-3- ylme...)
Affinity DataIC50: 0.800nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543121BDBM543121(3-{4-[(2-iodophenyl)sulfamoyl]phenyl}-1- (pyridin-...)
Affinity DataIC50: 0.800nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543114BDBM543114(3-{4-[(2-chloro-4- fluorophenyl)sulfamoyl]phenyl}-...)
Affinity DataIC50: 0.900nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543165BDBM543165(3-{4-[benzyl(ethyl)sulfamoyl]phenyl}-1- (pyridin-3...)
Affinity DataIC50: 0.900nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543149BDBM543149(3-{4-[(5-chloro-2- methoxyphenyl)sulfamoyl]phenyl}...)
Affinity DataIC50: 0.900nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543359BDBM543359(3-{4-[(3-chloro-4- methylbenzene)sulfonyl]phenyl}-...)
Affinity DataIC50: 0.900nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543108BDBM543108(3-{4-[(2,3-dimethylphenyl)sulfamoyl]phenyl}- 1-(py...)
Affinity DataIC50: 0.900nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543034BDBM543034(1-[4-(cyclohexylsulfamoyl)phenyl]-3- (pyridin-3-yl...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543229BDBM543229(US11279687, Compound 240 | 3-{4-[(2,3-dichlorobenz...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543233BDBM543233(US11279687, Compound 244 | 3-{4-[(2,4-difluorobenz...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543239BDBM543239(US11279687, Compound 250 | 3-{4-[(2,5- dimethoxybe...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543046BDBM543046(1-{4-[(naphthalen-1-yl)sulfamoyl]phenyl}-3- (pyrid...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543340BDBM543340(3-[4-(1-methyl-1H-indazole-4- sulfonyl)phenyl]-1-(...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543151BDBM543151(3-{4-[(5-fluoro-2-methoxyphenyl)sulfamoyl]phenyl]-...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543150BDBM543150(3-{4-[(5-chloro-2- methylphenyl)sulfamoyl]phenyl}-...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543159BDBM543159(3-{4-[4-(3-chloropyridin-2-yl)piperazine-1- sulfon...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543197BDBM543197(1-[4-(2H-1,3-benzodioxole-5- sulfonyl)phenyl]-3-(p...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543132BDBM543132(3-{4-[(3,5-dimethylphenyl)sulfamoyl]phenyl}- 1-(py...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 50435349BDBM50435349(CHEMBL2391585 | US11279687, Compound 208)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543262BDBM543262(3-{4-[(3,5- dimethylbenzene)sulfonyl]phenyl}-1- (p...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543329BDBM543329(3-(4-{[4-(ethoxymethyl)benzene]sulfonyl[phenyl)-1-...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543136BDBM543136(3-{4-[(3-chlorophenyl)sulfamoyl]phenyl]-1-(pyridin...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543075BDBM543075(3-(4-{8-methyl-2,8-diazaspiro[5.5]undecane- 2-sulf...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543267BDBM543267(3-{4-[(3-fluorobenzene)sulfonyl]phenyl}-1- (pyridi...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543266BDBM543266(3-{4-[(3-fluoro-4- methylbenzene)sulfonyl]phenyl}-...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543076BDBM543076(3-(4-{methyl[(1S)-1- phenylethyl]sulfamoyl}phenyl)...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543143BDBM543143(3-{4-[(4-chloro-2-methoxy-5- methylphenyl)sulfamoy...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543208BDBM543208(3-(4-{[2-fluoro-4-(1H-pyrazol-1- yl)benzene]sulfon...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543115BDBM543115(3-{4-[(2-chloro-4-methylphenyl) sulfamoyl]phenyl}-...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543181BDBM543181(N-methyl-2-[(4-{[(pyridin-3- ylmethyl)carbamoyl]am...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 50439675BDBM50439675(CHEMBL2417788 | US11279687, Compound 196)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543250BDBM543250(US11279687, Compound 261 | 3-{4-[(2-fluoro-3- meth...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543189BDBM543189(1-(pyridin-3-ylmethyl)-3-(4-{[3- (trifluoromethoxy...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543065BDBM543065(3-(4-{[3-chloro-4-(morpholin-4- yl)phenyl]sulfamoy...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543295BDBM543295(1-[4-(2,3-dihydro-1-benzofuran-7- sulfonyl)phenyl]...)
Affinity DataIC50: 1.10nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543166BDBM543166(3-{4-[benzyl(methyl)sulfamoyl]phenyl}-1- (pyridin-...)
Affinity DataIC50: 1.10nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543294BDBM543294(1-[4-(2,3-dihydro-1,4-benzodioxine-6- sulfonyl)phe...)
Affinity DataIC50: 1.10nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543326BDBM543326(3-(4-{[3-fluoro-5-(2,2,2-trifluoroethoxy)benzene]s...)
Affinity DataIC50: 1.10nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543363BDBM543363(3-{4-[(3- ethanesulfonamidobenzene)sulfonyl]phenyl...)
Affinity DataIC50: 1.10nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543309BDBM543309(2-methyl-N-{3-[(4-{[(pyridin-3-ylmethyl)carbamoyl]...)
Affinity DataIC50: 1.20nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543378BDBM543378(3-{4-[(4-ethoxy-3- fluorobenzene)sulfonyl]phenyl}-...)
Affinity DataIC50: 1.20nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543396BDBM543396(N,N-diethyl-3-fluoro-5-[(4-{[(pyridin-3-ylmethyl)c...)
Affinity DataIC50: 1.20nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543015BDBM543015(1-(pyridin-3-ylmethyl)-3-(4-{[2- (trifluoromethoxy...)
Affinity DataIC50: 1.20nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 543111BDBM543111(3-{4-[(2,5- dimethoxyphenyl)sulfamoyl]phenyl}-1- (...)
Affinity DataIC50: 1.20nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

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