Compile Data Set for Download or QSAR
Report error Found 794 Enz. Inhib. hit(s) with all data for entry = 10521
TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400313(US9999619, Example 68 | US10695337, Example 67 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400567(US9999619, Example 323 | US10695337, Example 323 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400568(US9999619, Example 324 | US10695337, Example 324 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400316(US9999619, Example 71 | US10695337, Example 70 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM448506(US10695337, Example 72 | {1-{1-[(4-methoxy-3- thie...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400572(4-{3-(Cyanomethyl)-3-[4-(5-fluoro-1H-pyrrolo[2,3-b...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400319(US9999619, Example 74 | US10695337, Example 73 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400320(US9999619, Example 75 | US10695337, Example 74 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400574(US9999619, Example 330 | US11285140, Example 330)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400305(US9999619, Example 60 | US10695337, Example 59 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400306(US9999619, Example 61 | US10695337, Example 60 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400560(US9999619, Example 316 | US10695337, Example 316 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400561(US9999619, Example 317 | US10695337, Example 317 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400309(US9999619, Example 64 | US10695337, Example 63 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400563(US9999619, Example 319 | US10695337, Example 319 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400310(US9999619, Example 65 | US10695337, Example 64 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400564(US9999619, Example 320 | US10695337, Example 320 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400311(US9999619, Example 66 | US10695337, Example 65 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400565(US9999619, Example 321 | US10695337, Example 321 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400566(US9999619, Example 322 | US10695337, Example 322 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400329(US9999619, Example 84 | US10695337, Example 83 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400330(US9999619, Example 85 | US10695337, Example 84 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400332(US9999619, Example 87 | US10695337, Example 86 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400586({1-{1-[5-Chloro-2-(trifluoromethyl)isonicotinoyl]p...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400333(US9999619, Example 88 | US10695337, Example 87 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400588([3-[4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400335(US9999619, Example 90 | US10695337, Example 89 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400336(US9999619, Example 91 | US10695337, Example 90 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400590([3-[3-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrrol-...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400321(US9999619, Example 76 | US10695337, Example 75 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400575(US9999619, Example 331 | US11285140, Example 331)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400322(US9999619, Example 77 | US10695337, Example 76 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400576(4-[1-(3-(Cyanomethyl)-1-{1-[3-fluoro-2-(trifluorom...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400323(US9999619, Example 78 | US10695337, Example 77 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400324(US9999619, Example 79 | US10695337, Example 78 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400315(US9999619, Example 70 | US10695337, Example 69 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400579(US9999619, Example 335 | US11285140, Example 335)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400326(US9999619, Example 81 | US10695337, Example 80 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400580(US9999619, Example 336 | US11285140, Example 336)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400327(US9999619, Example 82 | US10695337, Example 81 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400328(US9999619, Example 83 | US10695337, Example 82 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400599({3-[4-(5-Fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400601(4-(1-{3-(Cyanomethyl)-1-[1-(methylsulfonyl)piperid...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM246868({1-{1-[3-Fluoro-2- (trifluoromethyl) isonicotinoyl...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400603(US9999619, Example 360 | cis-{1-{3-Methoxy-1-[3-fl...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400603(US9999619, Example 360 | cis-{1-{3-Methoxy-1-[3-fl...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400605({1-{cis-3-Fluoro-1-[3-fluoro-2-(trifluoromethyl)is...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400606({1-(cis-3-Fluoro-1-{[2-(trifluoromethyl)pyrimidin-...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400337(US9999619, Example 92 | US10695337, Example 91 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM400338(US9999619, Example 93 | US10695337, Example 92 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

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