Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 10551
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549179BDBM549179((5R)-N2-ethyl-5-oxido-N4-tetrahydropyran-4-yl-N2-(...)
Affinity DataIC50: 10nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549305BDBM549305(2-chloro-N- cyclohexyl-5- oxido-6,7-dihydro- thien...)
Affinity DataIC50: 10nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549302BDBM549302(2-chloro-N-(1- methylcyclopropyl)- 5-oxido-6,7-dih...)
Affinity DataIC50: 10nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549301BDBM549301(2-chloro-N-[(1R)-1- methylpropyl]-5- oxido-6,7-dih...)
Affinity DataIC50: 10nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549180BDBM549180(N4-tert-butyl-N2-methyl-5-oxido-N2-(2-tetrahydropy...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549184BDBM549184(N4-isopropyl-N2- methyl-5-oxido-N2-(2- tetrahydrop...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549292BDBM549292(2-chloro-5-oxido-N- propyl-6,7-dihydro- thieno[3,2...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549291BDBM549291(N4-butyl-N2-methyl- 5-oxido-N2-(2- tetrahydropyran...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549294BDBM549294(N-butyl-2-chloro-5- oxido-6,7-dihydro- thieno[3,2-...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549293BDBM549293(2-chloro-N- isopropyl-5- oxido-6,7-dihydro- thieno...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549296BDBM549296(2-chloro-N-(1- methylcyclobutyl)- 5-oxido-6,7- dih...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549295BDBM549295(2-chloro-N- isobutyl-5-oxido- 6,7-dihydro- thieno[...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549298BDBM549298(1-[(2-chloro-5- oxido-6,7-dihydro- thieno[3,2-d]py...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549297BDBM549297(2-chloro-N- cyclobutyl-5- oxido-6,7-dihydro- thien...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549300BDBM549300(2-chloro-N-[(1S)-1- methylpropyl]-5- oxido-6,7-dih...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549299BDBM549299(1-[(2-chloro-5- oxido-6,7-dihydro- thieno[3,2-d]py...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549176BDBM549176((5R)-N2-methyl-5-oxido-N4-tetrahydropyran-4-yl-N2-...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549183BDBM549183(N2-methyl-5-oxido- N4-propyl-N2-(2- tetrahydropyra...)
Affinity DataIC50: 75nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549304BDBM549304(2-chloro-N-(3- methoxyphenyl)-5- oxido-6,7-dihydro...)
Affinity DataIC50: 100nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549303BDBM549303(2-chloro-N-(6- oxaspiro[3.3]heptan- 2-yl)-5-oxido-...)
Affinity DataIC50: 100nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549306BDBM549306(2-[(2-chloro-5- oxido-6,7-dihydro- thieno[3,2-d]py...)
Affinity DataIC50: 100nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549308BDBM549308(2-chloro-N- cyclopentyl-5- oxido-6,7-dihydro- thie...)
Affinity DataIC50: 100nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549307BDBM549307(2-chloro-N-ethyl-5- oxido-6,7-dihydro- thieno[3,2-...)
Affinity DataIC50: 100nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 549309BDBM549309(2-chloro-N-(oxetan- 3-yl)-5-oxido-6,7- dihydro- th...)
Affinity DataIC50: 100nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent