Compile Data Set for Download or QSAR
Report error Found 191 Enz. Inhib. hit(s) with all data for entry = 10601
TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553962BDBM553962(US11325906, Example 25)
Affinity DataIC50: 2nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553943BDBM553943(US11325906, Example 7)
Affinity DataIC50: 2nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553941BDBM553941(US11325906, Example 5)
Affinity DataIC50: 2nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553967BDBM553967(US11325906, Example 30)
Affinity DataIC50: 3nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553942BDBM553942(US11325906, Example 6)
Affinity DataIC50: 3nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553937BDBM553937(US11325906, Example 1)
Affinity DataIC50: 3nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553961BDBM553961(US11325906, Example 24)
Affinity DataIC50: 3nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553969BDBM553969(US11325906, Example 32)
Affinity DataIC50: 3nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553944BDBM553944(US11325906, Example 8)
Affinity DataIC50: 3nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553951BDBM553951(US11325906, Example 14)
Affinity DataIC50: 4nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553948BDBM553948(US11325906, Example 12)
Affinity DataIC50: 4nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553960BDBM553960(US11325906, Example 23)
Affinity DataIC50: 4nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553940BDBM553940(US11325906, Example 4 | US20250289800, Comparative...)
Affinity DataIC50: 4nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553958BDBM553958(US11325906, Example 21)
Affinity DataIC50: 4nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553966BDBM553966(US11325906, Example 29)
Affinity DataIC50: 4nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553938BDBM553938(US11325906, Example 2)
Affinity DataIC50: 4nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553947BDBM553947(US11325906, Example 11)
Affinity DataIC50: 5nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553939BDBM553939(US11325906, Example 3)
Affinity DataIC50: 5nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553968BDBM553968(US11325906, Example 31)
Affinity DataIC50: 5nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553963BDBM553963(US11325906, Example 26)
Affinity DataIC50: 5nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553946BDBM553946(US11325906, Example 10)
Affinity DataIC50: 5nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553959BDBM553959(US11325906, Example 22)
Affinity DataIC50: 6nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553965BDBM553965(US11325906, Example 28)
Affinity DataIC50: 6nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553964BDBM553964(US11325906, Example 27)
Affinity DataIC50: 7nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553954BDBM553954(US11325906, Example 17)
Affinity DataIC50: 7nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553950BDBM553950(US11325906, Example 13)
Affinity DataIC50: 7nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553953BDBM553953(US11325906, Example 16)
Affinity DataIC50: 7nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553945BDBM553945(US11325906, Example 9)
Affinity DataIC50: 9nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553952BDBM553952(US11325906, Example 15)
Affinity DataIC50: 11nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553957BDBM553957(US11325906, Example 20)
Affinity DataIC50: 14nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553956BDBM553956(US11325906, Example 19)
Affinity DataIC50: 15nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553955BDBM553955(US11325906, Example 18)
Affinity DataIC50: 31nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553941BDBM553941(US11325906, Example 5)
Affinity DataIC50: 650nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553942BDBM553942(US11325906, Example 6)
Affinity DataIC50: 840nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553938BDBM553938(US11325906, Example 2)
Affinity DataIC50: 880nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553959BDBM553959(US11325906, Example 22)
Affinity DataIC50: 1.00E+3nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553939BDBM553939(US11325906, Example 3)
Affinity DataIC50: 1.30E+3nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553943BDBM553943(US11325906, Example 7)
Affinity DataIC50: 1.30E+3nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553940BDBM553940(US11325906, Example 4 | US20250289800, Comparative...)
Affinity DataIC50: 1.50E+3nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553948BDBM553948(US11325906, Example 12)
Affinity DataIC50: 1.60E+3nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553937BDBM553937(US11325906, Example 1)
Affinity DataIC50: 1.70E+3nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553954BDBM553954(US11325906, Example 17)
Affinity DataIC50: 1.70E+3nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553969BDBM553969(US11325906, Example 32)
Affinity DataIC50: 1.90E+3nMAssay Description:PARP3: Recombinant full length PARP3 protein was diluted to 100 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553969BDBM553969(US11325906, Example 32)
Affinity DataIC50: 2.10E+3nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553959BDBM553959(US11325906, Example 22)
Affinity DataIC50: 2.60E+3nMAssay Description:PARP3: Recombinant full length PARP3 protein was diluted to 100 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553968BDBM553968(US11325906, Example 31)
Affinity DataIC50: 2.60E+3nMAssay Description:PARP3: Recombinant full length PARP3 protein was diluted to 100 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553943BDBM553943(US11325906, Example 7)
Affinity DataIC50: 2.60E+3nMAssay Description:PARP3: Recombinant full length PARP3 protein was diluted to 100 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553951BDBM553951(US11325906, Example 14)
Affinity DataIC50: 2.90E+3nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553953BDBM553953(US11325906, Example 16)
Affinity DataIC50: 3.30E+3nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 553952BDBM553952(US11325906, Example 15)
Affinity DataIC50: 3.60E+3nMAssay Description:PARP2: Recombinant full length PARP2 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

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