Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 10631
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555730BDBM555730(US11345676, Example 26 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555729BDBM555729(US11345676, Example 25 | US11345676, Compound 1-22...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555732BDBM555732(US11345676, Example 28 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555731BDBM555731(US11345676, Example 27 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555713BDBM555713(US11345676, Compound 1-338 | US11345676, Example 9...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555736BDBM555736(US11345676, Example 33 | US11345676, Compound 1-34...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555735BDBM555735(US11345676, Example 32 | US11345676, Compound 1-34...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555738BDBM555738(US11345676, Example 35 | US11345676, Compound 1-34...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555722BDBM555722(US11345676, Example 18 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 4: LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555726BDBM555726(US11345676, Example 22 | US11345676, Compound 2-1)
Affinity DataIC50: 300nMAssay Description:Table 4: LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555723BDBM555723(US11345676, Example 19 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 4: LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555714BDBM555714(US11345676, Example 10 | US11345676, Compound 1-30...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555713BDBM555713(US11345676, Compound 1-338 | US11345676, Example 9...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555716BDBM555716(US11345676, Example 12 | US11345676, Compound 1-30...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555715BDBM555715(US11345676, Example 11 | US11345676, Compound 1-30...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555718BDBM555718(US11345676, Example 14 | US11345676, Compound 1-31...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555717BDBM555717(US11345676, Example 13 | US11345676, Compound 1-30...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555720BDBM555720(US11345676, Example 16 | US11345676, Compound 1-31...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555719BDBM555719(US11345676, Example 15 | US11345676, Compound 1-31...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555722BDBM555722(US11345676, Example 18 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555724BDBM555724(US11345676, Example 20 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555723BDBM555723(US11345676, Example 19 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555725BDBM555725(US11345676, Example 21 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555727BDBM555727(US11345676, Example 23 | US11345676, Compound 1-22...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555706BDBM555706(US11345676, Example 2 | US11345676, Compound 1-23)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555705BDBM555705(US11345676, Example 1 | US11345676, Compound 1-179)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555708BDBM555708(US11345676, Example 4 | US11345676, Compound 1-181)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555710BDBM555710(US11345676, Example 6 | US11345676, Compound 1-211)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555709BDBM555709(US11345676, Example 5 | US11345676, Compound 1-210)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555712BDBM555712(US11345676, Example 8 | US11345676, Compound 1-217)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555711BDBM555711(US11345676, Example 7 | US11345676, Compound 1-213)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555733BDBM555733(US11345676, Example 29 | US11345676, Compound 1-33...)
Affinity DataIC50: 650nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555737BDBM555737(US11345676, Example 34 | US11345676, Compound 1-34...)
Affinity DataIC50: 650nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555721BDBM555721(US11345676, Example 17 | US11345676, Compound 1-32...)
Affinity DataIC50: 650nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555707BDBM555707(US11345676, Example 3 | US11345676, Compound 1-24)
Affinity DataIC50: 650nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555728BDBM555728(US11345676, Example 24 | US11345676, Compound 1-22...)
Affinity DataIC50: 650nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555714BDBM555714(US11345676, Example 10 | US11345676, Compound 1-30...)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 4: LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 555726BDBM555726(US11345676, Example 22 | US11345676, Compound 2-1)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent