Compile Data Set for Download or QSAR
maximum 50k data
Found 447 Enz. Inhib. hit(s) with all data for entry = 10664
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557850(6-((1-acryloylpiperidin-4-yl)oxy)-4-((3,4-dichloro...)
Affinity DataIC50:  0.130nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557852(1-(3-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  0.350nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557849(1-(3-((4-((3,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  0.510nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50468247(HM 781-36B | HM-781-36B | NOV-120101 | Poziotinib ...)
Affinity DataIC50:  0.910nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557852(1-(3-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  1.10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-770,'SVD',771-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557852(1-(3-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  1.10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-770,'SVD',771-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50468247(HM 781-36B | HM-781-36B | NOV-120101 | Poziotinib ...)
Affinity DataIC50:  1.70nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-769,'SV',770-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557852(1-(3-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  1.70nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-769,'SVD',770-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557852(1-(3-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  2nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557849(1-(3-((4-((3,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  2nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557865(1-(4-((4-((3,4-dichloro- phenyl)amino)-7-methoxy- ...)
Affinity DataIC50:  2nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-770,'SVD',771-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557849(1-(3-((4-((3,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  2.30nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50468247(HM 781-36B | HM-781-36B | NOV-120101 | Poziotinib ...)
Affinity DataIC50:  2.30nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-772,'NPH',773-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557849(1-(3-((4-((3,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  2.40nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557851(1-(3-((4-((2,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  2.5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-772,'NPH',773-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557852(1-(3-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  2.80nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557875(1-(3-((7-methoxy-4- (phenylamino)quinazolin-6- yl)...)
Affinity DataIC50:  2.90nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-769,'SV',770-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557849(1-(3-((4-((3,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  3nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-769,'SVD',770-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50468247(HM 781-36B | HM-781-36B | NOV-120101 | Poziotinib ...)
Affinity DataIC50:  3nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2 [1-780,'GSP',781-1255](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557849(1-(3-((4-((3,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  3.20nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-769,'SVD',770-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557849(1-(3-((4-((3,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  3.60nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557870(1-(3-((4-((3,4-dichloro-2- fluorophenyl)amino)-7- ...)
Affinity DataIC50:  3.90nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557858(6-((1-acryloylpiperidin-4- yl)oxy)-4-((4-bromo-3- ...)
Affinity DataIC50:  4nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557865(1-(4-((4-((3,4-dichloro- phenyl)amino)-7-methoxy- ...)
Affinity DataIC50:  4.20nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557868(1-(3-((4-((4-bromo-3- chlorophenyl)amino)-7- metho...)
Affinity DataIC50:  4.80nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557852(1-(3-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  4.90nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557872(1-(4-((4-((4-bromo-3- chlorophenyl)amino)-7- metho...)
Affinity DataIC50:  5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557846(1-(4-((4-((2,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50468247(HM 781-36B | HM-781-36B | NOV-120101 | Poziotinib ...)
Affinity DataIC50:  5.20nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-772,'NPH',773-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557850(6-((1-acryloylpiperidin-4-yl)oxy)-4-((3,4-dichloro...)
Affinity DataIC50:  5.90nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2 [1-780,'GSP',781-1255](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557865(1-(4-((4-((3,4-dichloro- phenyl)amino)-7-methoxy- ...)
Affinity DataIC50:  6.5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557867(1-(4-((7-methoxy-4-((3- (oxazol-5-yl)phenyl)- amin...)
Affinity DataIC50:  6.5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557898(1-(3-((4-((3,4-dichloro- phenyl)amino)-7-methoxy- ...)
Affinity DataIC50:  6.60nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557849(1-(3-((4-((3,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  7.10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557850(6-((1-acryloylpiperidin-4-yl)oxy)-4-((3,4-dichloro...)
Affinity DataIC50:  7.20nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-769,'SV',770-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50468247(HM 781-36B | HM-781-36B | NOV-120101 | Poziotinib ...)
Affinity DataIC50:  7.40nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557852(1-(3-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  7.40nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557869(1-(3-((4-((3-cyclopropyl- phenyl)amino)-7-methoxy-...)
Affinity DataIC50:  8.10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'VC',777-1255](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557849(1-(3-((4-((3,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  9.10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557868(1-(3-((4-((4-bromo-3- chlorophenyl)amino)-7- metho...)
Affinity DataIC50:  9.5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2 [1-780,'GSP',781-1255](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557852(1-(3-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  9.5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-770,'SVD',771-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557865(1-(4-((4-((3,4-dichloro- phenyl)amino)-7-methoxy- ...)
Affinity DataIC50:  10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557865(1-(4-((4-((3,4-dichloro- phenyl)amino)-7-methoxy- ...)
Affinity DataIC50:  10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-769,'SVD',770-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557850(6-((1-acryloylpiperidin-4-yl)oxy)-4-((3,4-dichloro...)
Affinity DataIC50:  10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-770,'SVD',771-1210](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557850(6-((1-acryloylpiperidin-4-yl)oxy)-4-((3,4-dichloro...)
Affinity DataIC50:  10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557849(1-(3-((4-((3,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557888(1-(3-((4-((4-bromo-3- chlorophenyl)amino)-7- metho...)
Affinity DataIC50:  10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557854(US11365189, Ex. No. 9)
Affinity DataIC50:  11nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2 [1-780,'GSP',781-1255](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557872(1-(4-((4-((4-bromo-3- chlorophenyl)amino)-7- metho...)
Affinity DataIC50:  11nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'VC',777-1255](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM557865(1-(4-((4-((3,4-dichloro- phenyl)amino)-7-methoxy- ...)
Affinity DataIC50:  11nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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