Compile Data Set for Download or QSAR
Report error Found 191 Enz. Inhib. hit(s) with all data for entry = 10690
TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365038BDBM365038(4-(3-(4-methoxybenzyl)-4,5- dihydro-3H-1,2,2a1,5- ...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365161BDBM365161(4-(3-(3-methoxybenzyl)-3,4- dihydro-5-oxa-1,2,2a1-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365036BDBM365036(4-(3-isobutyl-4,5-dihydro- 3H-1,2,2a1,5- tetraazaa...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365167BDBM365167(9-(2-fluoro-4- methoxybenzyl)-6-methyl-4- (2-((1-m...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383226BDBM383226(4-(3-(4-chlorobenzyl)-5- methyl-4,5-dihydro-3H- 1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365040BDBM365040(4-(3-(3-fluoro-4- methoxybenzyl)-4,5-dihydro- 3H-1...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365046BDBM365046(4-(3-benzyl-3,4-dihydro-5- oxa-1,2,2a1- triazaacen...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383227BDBM383227(4-(3-(4-chloro-3- fluorobenzyl)-4,5-dihydro- 3H-1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383354BDBM383354(N-(1-methyl-1H-pyrazol-5- yl)-4-(9-((4-(trifluorom...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383233BDBM383233(4-(3-benzyl-5-ethyl-4,5- dihydro-3H-1,2,2a1,5- tet...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383231BDBM383231(4-(3-benzyl-3,4-dihydro-5- thia-1,2,2a1- triazaace...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383352BDBM383352(4-(3-(3-chlorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 560007BDBM560007(US11376260, Example I-73S | N-(1-methyl-1H-pyrazol...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365149BDBM365149(9-(2-fluoro-4- methoxybenzyl)-6-methyl-4- (2-((1-m...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365153BDBM365153(4-(3-benzyl-4-methyl-3,4- dihydro-5-oxa-1,2,2a1- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365148BDBM365148(N-(1-methyl-1H-pyrazol-5- yl)-4-(9-((4-(trifluorom...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365025BDBM365025(N-(1-methyl-1H-pyrazol-5- yl)-4-(3-phenyl-4,5-dihy...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365147BDBM365147(4-(3-benzyl-4-methyl-3,4- dihydro-5-oxa-1,2,2a1- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365023BDBM365023(N-(1-methyl-1H-pyrazol-5- yl)-4-(3-phenyl-4,5-dihy...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365153BDBM365153(4-(3-benzyl-4-methyl-3,4- dihydro-5-oxa-1,2,2a1- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365030BDBM365030(4-(3-benzyl-4,5-dihydro-3H- 1,2,2a1,5- tetraazaace...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365027BDBM365027(4-(3-(4-chlorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365154BDBM365154(4-(3-benzyl-4-methyl-3,4- dihydro-5-oxa-1,2,2a1- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383337BDBM383337(4-(9-((5-chloropyridin-3- yl)oxy)-8,9-dihydro-7H-6...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365034BDBM365034(4-(3-benzyl-5-methyl-4,5- dihydro-3H-1,2,2a1,5- te...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383335BDBM383335(4-(9-((5-chloropyridin-3- yl)oxy)-8,9-dihydro-7H-6...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 365032BDBM365032(4-(3-(4-chlorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383373BDBM383373(N-(1-methyl-1H-pyrazol-5- yl)-4-(9-propyl-8,9-dihy...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 560058BDBM560058(US11376260, Example I-105S | (S)-2-[4-(2-((1-methy...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383251BDBM383251(4-(9-((benzyloxy)methyl)- 8,9-dihydro-7H-6-oxa- 1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 559931BDBM559931(US11376260, Example I-32S | 4-(3-(4-chloro-3-fluor...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383254BDBM383254(4-(9-(2-chlorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383255BDBM383255(4-(3-(4-fluorobenzyl)-5- methyl-4,5-dihydro-3H- 1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383260BDBM383260(4-(9-(4-chlorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383314BDBM383314(US10278975, Compound I-108 S | 4-(9-(4-fluoropheno...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383264BDBM383264(9-(4-chlorobenzyl)-6-methyl- 4-(2-((1-methyl-1H-py...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383385BDBM383385(4-(9-(3,4-difluorophenoxy)- 8,9-dihydro-7H-6-oxa- ...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383261BDBM383261(4-(3-benzyl-3,4-dihydro-5- oxa-1,2,2a1- triazaacen...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 560066BDBM560066(US11376260, Example I-109R | N-(1-methyl-1H-pyrazo...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383383BDBM383383(4-(9-((4-chloro-1H-pyrazol-1- yl)methyl)-8,9-dihyd...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383355BDBM383355(N-(1-methyl-1H-pyrazol-5- yl)-4-(9-phenoxy-8,9- di...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383240BDBM383240(4-(3-(4-fluorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383361BDBM383361(N-(1-methyl-1H-pyrazol-5- yl)-4-(9-((3-methylisoxa...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383245BDBM383245(4-(3-((6-methoxypyridin-3- yl)methyl)-4,5-dihydro3...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383242BDBM383242(9-(4-chlorobenzyl)-6-methyl- 4-(2-((1-methyl-1H-py...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383365BDBM383365(4-(3-(3-methoxybenzyl)-3,4- dihydro-5-oxa-1,2,2a1-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383284BDBM383284(4-(3-(4-methoxybenzyl)-3,4- dihydro-5-oxa-1,2,2a1-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383282BDBM383282(4-(3-(3-fluoro-4- methoxybenzyl)-3,4-dihydro- 5-ox...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383288BDBM383288(4-(3-(3,4-difluorobenzyl)-3,4- dihydro-5-oxa-1,2,2...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383286BDBM383286(N-(1-methyl-1H-pyrazol-5- yl)-4-(3-(2-methylbutyl)...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent

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