Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 10773
TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 437978BDBM437978(US10618886, Compound I | US10730853, Compound I | ...)
Affinity DataIC50: 1.73nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 437978BDBM437978(US10618886, Compound I | US10730853, Compound I | ...)
Affinity DataIC50: 3.05nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438108BDBM438108(US10618886, Compound II | US10730853, Compound XII...)
Affinity DataIC50: 3.18nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438114BDBM438114(US10618886, Compound VII | US10730853, Compound VI...)
Affinity DataIC50: 3.44nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438108BDBM438108(US10618886, Compound II | US10730853, Compound XII...)
Affinity DataIC50: 3.63nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438112BDBM438112(US10618886, Compound VI | US10730853, Compound IX ...)
Affinity DataIC50: 3.83nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438110BDBM438110(US10618886, Compound IV | US10730853, Compound IV ...)
Affinity DataIC50: 3.87nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438115BDBM438115(US10618886, Compound VIII | US10730853, Compound V...)
Affinity DataIC50: 4.81nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438119BDBM438119(US10618886, Compound XII | US11420955, Compound XI...)
Affinity DataIC50: 4.97nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 453705BDBM453705(US10730853, Compound VI | US11420955, Compound VI)
Affinity DataIC50: 5.36nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 453705BDBM453705(US10730853, Compound VI | US11420955, Compound VI)
Affinity DataIC50: 5.5nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438120BDBM438120(US10618886, Compound XIII | US10730853, Compound X...)
Affinity DataIC50: 5.63nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438115BDBM438115(US10618886, Compound VIII | US10730853, Compound V...)
Affinity DataIC50: 6.11nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438112BDBM438112(US10618886, Compound VI | US10730853, Compound IX ...)
Affinity DataIC50: 7.70nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438110BDBM438110(US10618886, Compound IV | US10730853, Compound IV ...)
Affinity DataIC50: 8.15nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438117BDBM438117(US10618886, Compound X | US10730853, Compound X | ...)
Affinity DataIC50: 9.10nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438114BDBM438114(US10618886, Compound VII | US10730853, Compound VI...)
Affinity DataIC50: 10.5nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438120BDBM438120(US10618886, Compound XIII | US10730853, Compound X...)
Affinity DataIC50: 10.9nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438119BDBM438119(US10618886, Compound XII | US11420955, Compound XI...)
Affinity DataIC50: 17.6nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438111BDBM438111(US10618886, Compound IX | US10618886, Compound V |...)
Affinity DataIC50: 20nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438109BDBM438109(US10618886, Compound III | US10730853, Compound II...)
Affinity DataIC50: 21.2nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438111BDBM438111(US10618886, Compound IX | US10618886, Compound V |...)
Affinity DataIC50: 36.5nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438109BDBM438109(US10618886, Compound III | US10730853, Compound II...)
Affinity DataIC50: 39.6nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438125BDBM438125(US10618886, Compound XX | US10730853, Compound XX ...)
Affinity DataIC50: 50.5nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438117BDBM438117(US10618886, Compound X | US10730853, Compound X | ...)
Affinity DataIC50: 52.5nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 453716BDBM453716(US10730853, Compound XIV | US11420955, Compound XI...)
Affinity DataIC50: 55.7nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 453716BDBM453716(US10730853, Compound XIV | US11420955, Compound XI...)
Affinity DataIC50: 61.9nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 453717BDBM453717(US10730853, Compound XVI | US11420955, Compound XV...)
Affinity DataIC50: 116nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 453717BDBM453717(US10730853, Compound XVI | US11420955, Compound XV...)
Affinity DataIC50: 175nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438127BDBM438127(US10618886, Compound XXII | US10730853, Compound X...)
Affinity DataIC50: 229nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438127BDBM438127(US10618886, Compound XXII | US10730853, Compound X...)
Affinity DataIC50: 242nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438126BDBM438126(US10618886, Compound XXI | US10730853, Compound XX...)
Affinity DataIC50: 286nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438125BDBM438125(US10618886, Compound XX | US10730853, Compound XX ...)
Affinity DataIC50: 814nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438124BDBM438124(US10618886, Compound XIX | US10730853, Compound XI...)
Affinity DataIC50: 1.00E+3nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438124BDBM438124(US10618886, Compound XIX | US10730853, Compound XI...)
Affinity DataIC50: 1.00E+3nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xwpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 438126BDBM438126(US10618886, Compound XXI | US10730853, Compound XX...)
Affinity DataIC50: 1.00E+3nMAssay Description:Experimental procedure: 1) Membrane preparation for HEK293/Ga15/hH3R; 2) Standard binding assay. Briefly, for membrane parathion, HEK293/Ga15/hH3R ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent